Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression

Lysophosphatidic acid receptors (LPARs) are six G-protein-coupled receptors that mediate LPA signaling to promote tumorigenesis and therapy resistance in many cancer subtypes, including breast cancer. Individual-receptor-targeted monotherapies are under investigation, but receptor agonism or antagon...

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Detalles Bibliográficos
Autores principales: Benesch, Matthew G. K., Wu, Rongrong, Tang, Xiaoyun, Brindley, David N., Ishikawa, Takashi, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298074/
https://www.ncbi.nlm.nih.gov/pubmed/37372960
http://dx.doi.org/10.3390/ijms24129812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298074/
https://www.ncbi.nlm.nih.gov/pubmed/37372960
http://dx.doi.org/10.3390/ijms24129812

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