Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type

Spinal deformity in Ehlers–Danlos syndrome (EDS) is an important symptom that can lead to trunk balance deterioration, respiratory dysfunction, and digestive disorders as the deformity progresses, thereby reducing a patient’s quality of life and activities of daily living. The severity of the deform...

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Detalles Bibliográficos
Autores principales: Uehara, Masashi, Takahashi, Jun, Kosho, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298114/
https://www.ncbi.nlm.nih.gov/pubmed/37372353
http://dx.doi.org/10.3390/genes14061173
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author Uehara, Masashi
Takahashi, Jun
Kosho, Tomoki
author_facet Uehara, Masashi
Takahashi, Jun
Kosho, Tomoki
author_sort Uehara, Masashi
collection PubMed
description Spinal deformity in Ehlers–Danlos syndrome (EDS) is an important symptom that can lead to trunk balance deterioration, respiratory dysfunction, and digestive disorders as the deformity progresses, thereby reducing a patient’s quality of life and activities of daily living. The severity of the deformity varies widely, with treatment depending on the extent and the presence of associated complications. The present review addressed the current state of clinical research and treatment of spinal deformities in EDS with a specific focus on the musculocontractural type. Further studies are needed to better understand the underlying mechanisms of spinal deformity in EDS.
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spelling pubmed-102981142023-06-28 Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type Uehara, Masashi Takahashi, Jun Kosho, Tomoki Genes (Basel) Review Spinal deformity in Ehlers–Danlos syndrome (EDS) is an important symptom that can lead to trunk balance deterioration, respiratory dysfunction, and digestive disorders as the deformity progresses, thereby reducing a patient’s quality of life and activities of daily living. The severity of the deformity varies widely, with treatment depending on the extent and the presence of associated complications. The present review addressed the current state of clinical research and treatment of spinal deformities in EDS with a specific focus on the musculocontractural type. Further studies are needed to better understand the underlying mechanisms of spinal deformity in EDS. MDPI 2023-05-27 /pmc/articles/PMC10298114/ /pubmed/37372353 http://dx.doi.org/10.3390/genes14061173 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Uehara, Masashi
Takahashi, Jun
Kosho, Tomoki
Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title_full Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title_fullStr Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title_full_unstemmed Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title_short Spinal Deformity in Ehlers–Danlos Syndrome: Focus on Musculocontractural Type
title_sort spinal deformity in ehlers–danlos syndrome: focus on musculocontractural type
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298114/
https://www.ncbi.nlm.nih.gov/pubmed/37372353
http://dx.doi.org/10.3390/genes14061173
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AT koshotomoki spinaldeformityinehlersdanlossyndromefocusonmusculocontracturaltype

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