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Classification of Acute Myeloid Leukemia by Cell-Free DNA 5-Hydroxymethylcytosine

Epigenetic abnormality is a hallmark of acute myeloid leukemia (AML), and aberrant 5-hydroxymethylcytosine (5hmC) levels are commonly observed in AML patients. As epigenetic subgroups of AML correlate with different clinical outcomes, we investigated whether plasma cell-free DNA (cfDNA) 5hmC could c...

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Detalles Bibliográficos
Autores principales: Shao, Jianming, Shah, Shilpan, Ganguly, Siddhartha, Zu, Youli, He, Chuan, Li, Zejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298116/
https://www.ncbi.nlm.nih.gov/pubmed/37372359
http://dx.doi.org/10.3390/genes14061180