Carbonic Anhydrase IX Suppression Shifts Partial Response to Checkpoint Inhibitors into Complete Tumor Eradication: Model-Based Investigation

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of solid malignancies, including non-small-cell lung cancer. However, immunotherapy resistance constitutes a significant challenge. To investigate carbonic anhydrase IX (CAIX) as a driver of resistance, we built a differential equ...

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Detalles Bibliográficos
Autores principales: Grajek, Julia, Poleszczuk, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298206/
https://www.ncbi.nlm.nih.gov/pubmed/37373220
http://dx.doi.org/10.3390/ijms241210068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298206/
https://www.ncbi.nlm.nih.gov/pubmed/37373220
http://dx.doi.org/10.3390/ijms241210068

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