Cargando…
Folate and Cobalamin Deficiencies during Pregnancy Disrupt the Glucocorticoid Response in Hypothalamus through N-Homocysteinilation of the Glucocorticoid Receptor
Vitamin B9 (folate)/B12 (cobalamin) deficiency is known to induce brain structural and/or functional retardations. In many countries, folate supplementation, targeting the most severe outcomes such as neural tube defects, is discontinued after the first trimester. However, adverse effects may occur...
Autores principales: | Michel, Arnaud, Kokten, Tunay, Saber-Cherif, Lynda, Umoret, Rémy, Alberto, Jean-Marc, Helle, Déborah, Julien, Amélia, Daval, Jean-Luc, Guéant, Jean-Louis, Bossenmeyer-Pourié, Carine, Pourié, Grégory |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298228/ https://www.ncbi.nlm.nih.gov/pubmed/37372992 http://dx.doi.org/10.3390/ijms24129847 |
Ejemplares similares
-
Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus
por: Saber Cherif, Lynda, et al.
Publicado: (2019) -
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid
por: Geoffroy, Andréa, et al.
Publicado: (2019) -
Brain Susceptibility to Methyl Donor Deficiency: From Fetal Programming to Aging Outcome in Rats
por: Hassan, Ziad, et al.
Publicado: (2019) -
Late Maternal Folate Supplementation Rescues from Methyl Donor Deficiency-Associated Brain Defects by Restoring Let-7 and miR-34 Pathways
por: Geoffroy, Andréa, et al.
Publicado: (2016) -
The Stimulation of Neurogenesis Improves the Cognitive Status of Aging Rats Subjected to Gestational and Perinatal Deficiency of B9–12 Vitamins
por: Pourié, Grégory, et al.
Publicado: (2020)