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Folate and Cobalamin Deficiencies during Pregnancy Disrupt the Glucocorticoid Response in Hypothalamus through N-Homocysteinilation of the Glucocorticoid Receptor

Vitamin B9 (folate)/B12 (cobalamin) deficiency is known to induce brain structural and/or functional retardations. In many countries, folate supplementation, targeting the most severe outcomes such as neural tube defects, is discontinued after the first trimester. However, adverse effects may occur...

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Detalles Bibliográficos
Autores principales: Michel, Arnaud, Kokten, Tunay, Saber-Cherif, Lynda, Umoret, Rémy, Alberto, Jean-Marc, Helle, Déborah, Julien, Amélia, Daval, Jean-Luc, Guéant, Jean-Louis, Bossenmeyer-Pourié, Carine, Pourié, Grégory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298228/
https://www.ncbi.nlm.nih.gov/pubmed/37372992
http://dx.doi.org/10.3390/ijms24129847

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