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Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil

Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeaste...

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Autores principales: dos Santos, Natalia Bahia Pinheiro, de Paula Filho, Márcio Fabrício Falcão, Silva, Abigail Marcelino dos Santos, Teló, Enio Paulo, Junior, José Bandeira do Nascimento, de Queiroz Balbino, Valdir, Takenami, Iukary Oliveira, Cansanção, Isaac Farias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298256/
https://www.ncbi.nlm.nih.gov/pubmed/37372365
http://dx.doi.org/10.3390/genes14061185
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author dos Santos, Natalia Bahia Pinheiro
de Paula Filho, Márcio Fabrício Falcão
Silva, Abigail Marcelino dos Santos
Teló, Enio Paulo
Junior, José Bandeira do Nascimento
de Queiroz Balbino, Valdir
Takenami, Iukary Oliveira
Cansanção, Isaac Farias
author_facet dos Santos, Natalia Bahia Pinheiro
de Paula Filho, Márcio Fabrício Falcão
Silva, Abigail Marcelino dos Santos
Teló, Enio Paulo
Junior, José Bandeira do Nascimento
de Queiroz Balbino, Valdir
Takenami, Iukary Oliveira
Cansanção, Isaac Farias
author_sort dos Santos, Natalia Bahia Pinheiro
collection PubMed
description Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeastern Brazil. Thus, the present study aimed to identify the allele frequency distribution, in addition to the forensic and genetic data, of 25 STR loci in the population of Bahia. Buccal swabs or fingertip punctures were utilized to amplify and detect 25 DNA markers. The most polymorphic loci were SE33 (43), D21S11, and FGA (21). The least polymorphic were TH01 (6), TPOX, and D3S1358 (7). Forensic and statistical data were obtained through data analysis, which revealed a large genetic diversity, with an average value of 0.813 for the analyzed population. The present study was more robust than previous STR marker studies and will contribute to future research on population genetics in Brazil and worldwide. The results of this study allowed the establishment of haplotypes found in the forensic samples of Bahia State to serve as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary investigations.
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spelling pubmed-102982562023-06-28 Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil dos Santos, Natalia Bahia Pinheiro de Paula Filho, Márcio Fabrício Falcão Silva, Abigail Marcelino dos Santos Teló, Enio Paulo Junior, José Bandeira do Nascimento de Queiroz Balbino, Valdir Takenami, Iukary Oliveira Cansanção, Isaac Farias Genes (Basel) Article Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeastern Brazil. Thus, the present study aimed to identify the allele frequency distribution, in addition to the forensic and genetic data, of 25 STR loci in the population of Bahia. Buccal swabs or fingertip punctures were utilized to amplify and detect 25 DNA markers. The most polymorphic loci were SE33 (43), D21S11, and FGA (21). The least polymorphic were TH01 (6), TPOX, and D3S1358 (7). Forensic and statistical data were obtained through data analysis, which revealed a large genetic diversity, with an average value of 0.813 for the analyzed population. The present study was more robust than previous STR marker studies and will contribute to future research on population genetics in Brazil and worldwide. The results of this study allowed the establishment of haplotypes found in the forensic samples of Bahia State to serve as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary investigations. MDPI 2023-05-29 /pmc/articles/PMC10298256/ /pubmed/37372365 http://dx.doi.org/10.3390/genes14061185 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
dos Santos, Natalia Bahia Pinheiro
de Paula Filho, Márcio Fabrício Falcão
Silva, Abigail Marcelino dos Santos
Teló, Enio Paulo
Junior, José Bandeira do Nascimento
de Queiroz Balbino, Valdir
Takenami, Iukary Oliveira
Cansanção, Isaac Farias
Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title_full Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title_fullStr Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title_full_unstemmed Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title_short Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
title_sort allele frequencies and forensic data of 25 str markers for individuals in northeast brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298256/
https://www.ncbi.nlm.nih.gov/pubmed/37372365
http://dx.doi.org/10.3390/genes14061185
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