Cargando…
Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil
Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeaste...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298256/ https://www.ncbi.nlm.nih.gov/pubmed/37372365 http://dx.doi.org/10.3390/genes14061185 |
_version_ | 1785064070586564608 |
---|---|
author | dos Santos, Natalia Bahia Pinheiro de Paula Filho, Márcio Fabrício Falcão Silva, Abigail Marcelino dos Santos Teló, Enio Paulo Junior, José Bandeira do Nascimento de Queiroz Balbino, Valdir Takenami, Iukary Oliveira Cansanção, Isaac Farias |
author_facet | dos Santos, Natalia Bahia Pinheiro de Paula Filho, Márcio Fabrício Falcão Silva, Abigail Marcelino dos Santos Teló, Enio Paulo Junior, José Bandeira do Nascimento de Queiroz Balbino, Valdir Takenami, Iukary Oliveira Cansanção, Isaac Farias |
author_sort | dos Santos, Natalia Bahia Pinheiro |
collection | PubMed |
description | Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeastern Brazil. Thus, the present study aimed to identify the allele frequency distribution, in addition to the forensic and genetic data, of 25 STR loci in the population of Bahia. Buccal swabs or fingertip punctures were utilized to amplify and detect 25 DNA markers. The most polymorphic loci were SE33 (43), D21S11, and FGA (21). The least polymorphic were TH01 (6), TPOX, and D3S1358 (7). Forensic and statistical data were obtained through data analysis, which revealed a large genetic diversity, with an average value of 0.813 for the analyzed population. The present study was more robust than previous STR marker studies and will contribute to future research on population genetics in Brazil and worldwide. The results of this study allowed the establishment of haplotypes found in the forensic samples of Bahia State to serve as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary investigations. |
format | Online Article Text |
id | pubmed-10298256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102982562023-06-28 Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil dos Santos, Natalia Bahia Pinheiro de Paula Filho, Márcio Fabrício Falcão Silva, Abigail Marcelino dos Santos Teló, Enio Paulo Junior, José Bandeira do Nascimento de Queiroz Balbino, Valdir Takenami, Iukary Oliveira Cansanção, Isaac Farias Genes (Basel) Article Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeastern Brazil. Thus, the present study aimed to identify the allele frequency distribution, in addition to the forensic and genetic data, of 25 STR loci in the population of Bahia. Buccal swabs or fingertip punctures were utilized to amplify and detect 25 DNA markers. The most polymorphic loci were SE33 (43), D21S11, and FGA (21). The least polymorphic were TH01 (6), TPOX, and D3S1358 (7). Forensic and statistical data were obtained through data analysis, which revealed a large genetic diversity, with an average value of 0.813 for the analyzed population. The present study was more robust than previous STR marker studies and will contribute to future research on population genetics in Brazil and worldwide. The results of this study allowed the establishment of haplotypes found in the forensic samples of Bahia State to serve as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary investigations. MDPI 2023-05-29 /pmc/articles/PMC10298256/ /pubmed/37372365 http://dx.doi.org/10.3390/genes14061185 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article dos Santos, Natalia Bahia Pinheiro de Paula Filho, Márcio Fabrício Falcão Silva, Abigail Marcelino dos Santos Teló, Enio Paulo Junior, José Bandeira do Nascimento de Queiroz Balbino, Valdir Takenami, Iukary Oliveira Cansanção, Isaac Farias Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title | Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title_full | Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title_fullStr | Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title_full_unstemmed | Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title_short | Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil |
title_sort | allele frequencies and forensic data of 25 str markers for individuals in northeast brazil |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298256/ https://www.ncbi.nlm.nih.gov/pubmed/37372365 http://dx.doi.org/10.3390/genes14061185 |
work_keys_str_mv | AT dossantosnataliabahiapinheiro allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT depaulafilhomarciofabriciofalcao allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT silvaabigailmarcelinodossantos allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT teloeniopaulo allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT juniorjosebandeiradonascimento allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT dequeirozbalbinovaldir allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT takenamiiukaryoliveira allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil AT cansancaoisaacfarias allelefrequenciesandforensicdataof25strmarkersforindividualsinnortheastbrazil |