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Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats
CACNA1C encodes the pore-forming α1C subunit of the L-type Ca(2+) channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c(+/−) rats represent a recently developed model with a behavioral phenotype, but its cardiac p...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298289/ https://www.ncbi.nlm.nih.gov/pubmed/37372947 http://dx.doi.org/10.3390/ijms24129795 |