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Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats

CACNA1C encodes the pore-forming α1C subunit of the L-type Ca(2+) channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c(+/−) rats represent a recently developed model with a behavioral phenotype, but its cardiac p...

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Detalles Bibliográficos
Autores principales:	Fender, Hauke, Walter, Kim, Kiper, Aytug K., Plačkić, Jelena, Kisko, Theresa M., Braun, Moria D., Schwarting, Rainer K. W., Rohrbach, Susanne, Wöhr, Markus, Decher, Niels, Kockskämper, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298289/ https://www.ncbi.nlm.nih.gov/pubmed/37372947 http://dx.doi.org/10.3390/ijms24129795

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