Optimization of Mass Spectrometry Imaging for Drug Metabolism and Distribution Studies in the Zebrafish Larvae Model: A Case Study with the Opioid Antagonist Naloxone

Zebrafish (ZF; Danio rerio) larvae have emerged as a promising in vivo model in drug metabolism studies. Here, we set out to ready this model for integrated mass spectrometry imaging (MSI) to comprehensively study the spatial distribution of drugs and their metabolites inside ZF larvae. In our pilot...

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Detalles Bibliográficos
Autores principales: Park, Yu Mi, Meyer, Markus R., Müller, Rolf, Herrmann, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298338/
https://www.ncbi.nlm.nih.gov/pubmed/37373226
http://dx.doi.org/10.3390/ijms241210076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298338/
https://www.ncbi.nlm.nih.gov/pubmed/37373226
http://dx.doi.org/10.3390/ijms241210076

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