Atg4b Overexpression Extends Lifespan and Healthspan in Drosophila melanogaster

Autophagy plays important but complex roles in aging, affecting health and longevity. We found that, in the general population, the levels of ATG4B and ATG4D decreased during aging, yet they are upregulated in centenarians, suggesting that overexpression of ATG4 members could be positive for healths...

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Detalles Bibliográficos
Autores principales: Li, Yongxuan, Zhang, Wei, Ye, Yunshuang, Sun, Yinan, Yang, Liping, Chen, Guijun, Chen, Kangning, Smith, Sheryl, Zhou, Jumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298381/
https://www.ncbi.nlm.nih.gov/pubmed/37373039
http://dx.doi.org/10.3390/ijms24129893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298381/
https://www.ncbi.nlm.nih.gov/pubmed/37373039
http://dx.doi.org/10.3390/ijms24129893

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