Cargando…

Atg4b Overexpression Extends Lifespan and Healthspan in Drosophila melanogaster

Autophagy plays important but complex roles in aging, affecting health and longevity. We found that, in the general population, the levels of ATG4B and ATG4D decreased during aging, yet they are upregulated in centenarians, suggesting that overexpression of ATG4 members could be positive for healths...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yongxuan, Zhang, Wei, Ye, Yunshuang, Sun, Yinan, Yang, Liping, Chen, Guijun, Chen, Kangning, Smith, Sheryl, Zhou, Jumin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298381/ https://www.ncbi.nlm.nih.gov/pubmed/37373039 http://dx.doi.org/10.3390/ijms24129893

Ejemplares similares

Protein Restriction Effects on Healthspan and Lifespan in Drosophila melanogaster Are Additive With a Longevity-Promoting Diet
por: Zhang, Wei, et al.
Publicado: (2023)

dNAGLU Extends Life Span and Promotes Fitness and Stress Resistance in Drosophila
por: Xue, Rubing, et al.
Publicado: (2022)

Cinnamaldehyde Improves Lifespan and Healthspan in Drosophila melanogaster Models for Alzheimer's Disease
por: Pham, Hanh M., et al.
Publicado: (2018)

Soft-Shelled Turtle Peptides Extend Lifespan and Healthspan in Drosophila
por: Wang, Qianqian, et al.
Publicado: (2022)

The circadian clock gene period extends healthspan in aging Drosophila melanogaster
por: Krishnan, Natraj, et al.
Publicado: (2009)

Angelica keiskei Impacts the Lifespan and Healthspan of Drosophila melanogaster in a Sex and Strain-Dependent Manner
por: Jafari, Mahtab, et al.
Publicado: (2023)

Overexpression of Atg5 in mice activates autophagy and extends lifespan
por: Pyo, Jong-Ok, et al.
Publicado: (2013)

Overexpression of Fatty-Acid-β-Oxidation-Related Genes Extends the Lifespan of Drosophila melanogaster
por: Lee, Shin-Hae, et al.
Publicado: (2012)

Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster
por: Moskalev, Alexey, et al.
Publicado: (2019)

Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster
por: Nguyen, Nga N., et al.
Publicado: (2019)

Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster
por: Avanesian, Agnesa, et al.
Publicado: (2009)

EPIGENETIC PREDICTORS OF LIFESPAN AND HEALTHSPAN
por: Lu, Ake T, et al.
Publicado: (2019)

Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
por: Si, Hongbin, et al.
Publicado: (2019)

Parental age effect on the longevity and healthspan in Drosophila melanogaster and Caenorhabditis elegans
por: Lenzi, Camille, et al.
Publicado: (2023)

Dietary Restriction Extends Lifespan in Wild-Derived Populations of Drosophila melanogaster
por: Metaxakis, Athanasios, et al.
Publicado: (2013)

An epigenetic biomarker of aging for lifespan and healthspan
por: Levine, Morgan E., et al.
Publicado: (2018)

Metformin improves healthspan and lifespan in mice
por: Martin-Montalvo, Alejandro, et al.
Publicado: (2013)

Rebaudioside A Enhances Resistance to Oxidative Stress and Extends Lifespan and Healthspan in Caenorhabditis elegans
por: Li, Pan, et al.
Publicado: (2021)

Promoting healthspan and lifespan with caloric restriction in primates
por: Pifferi, Fabien, et al.
Publicado: (2019)

EPIGENETICS OF STRESS AND ADAPTATION ACROSS HEALTHSPAN AND LIFESPAN
por: Ferrucci, Luigi, et al.
Publicado: (2019)

Resilience as a Determinant of Healthspan and Lifespan in Mice
por: LeBrasseur, Nathan
Publicado: (2021)

Nutrient-Response Pathways in Healthspan and Lifespan Regulation
por: Dabrowska, Aleksandra, et al.
Publicado: (2022)

ADIPOCYTE-DERIVED FACTORS: IMPACT ON HEALTHSPAN AND LIFESPAN
por: Scherer, Philipp
Publicado: (2022)

The Ubx Polycomb response element bypasses an unpaired Fab-8 insulator via cis transvection in Drosophila
por: Lu, Danfeng, et al.
Publicado: (2018)

Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan
por: Vora, Mehul, et al.
Publicado: (2013)

Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice
por: Pathak, Shilpa, et al.
Publicado: (2020)

Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans
por: Matei, Ioan Valentin, et al.
Publicado: (2021)

Feeding, fecundity and lifespan in female Drosophila melanogaster
por: Barnes, Andrew I, et al.
Publicado: (2008)

Lifespan Extension by the Antioxidant Curcumin in Drosophila Melanogaster
por: Suckow, Brianne K., et al.
Publicado: (2006)

The role of commensal microbes in the lifespan of Drosophila melanogaster
por: Lee, Hye-Yeon, et al.
Publicado: (2019)

Sirt6 regulates lifespan in Drosophila melanogaster
por: Taylor, Jackson R., et al.
Publicado: (2022)

Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster
por: Shaposhnikov, Mikhail, et al.
Publicado: (2018)

Bats: Secrets of Extended Healthspan
por: Teeling, Emma
Publicado: (2021)

Prenatal hyperbaric normoxia treatment improves healthspan and regulates chitin metabolic genes in Drosophila melanogaster
por: Yu, Suyeun, et al.
Publicado: (2016)

Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status
por: Lee, Byung Cheon, et al.
Publicado: (2014)

Near-infrared light increases ATP, extends lifespan and improves mobility in aged Drosophila melanogaster
por: Begum, Rana, et al.
Publicado: (2015)

Ilex paraguariensis extracts extend the lifespan of Drosophila melanogaster fed a high-fat diet
por: Colpo, A.C., et al.
Publicado: (2017)

Chronobiotics KL001 and KS15 Extend Lifespan and Modify Circadian Rhythms of Drosophila melanogaster
por: Solovev, Ilya A., et al.
Publicado: (2021)

Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster
por: Hodge, Brian A., et al.
Publicado: (2022)

Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster
por: Aiello, Giuseppe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jk5mcvtqdsecvnu69jves2c63t