Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer

Bispecific antibodies are a promising type of therapy for the treatment of cancer due to their ability to simultaneously inhibit different proteins playing a role in cancer progression. The development in lung cancer has been singularly intense because of the increasingly vast knowledge of the under...

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Detalles Bibliográficos
Autores principales: Arasanz, Hugo, Chocarro, Luisa, Fernández-Rubio, Leticia, Blanco, Ester, Bocanegra, Ana, Echaide, Miriam, Labiano, Ibone, Huerta, Ana Elsa, Alsina, Maria, Vera, Ruth, Escors, David, Kochan, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298459/
https://www.ncbi.nlm.nih.gov/pubmed/37373003
http://dx.doi.org/10.3390/ijms24129855
Descripción
Sumario:Bispecific antibodies are a promising type of therapy for the treatment of cancer due to their ability to simultaneously inhibit different proteins playing a role in cancer progression. The development in lung cancer has been singularly intense because of the increasingly vast knowledge of the underlying molecular routes, in particular, in oncogene-driven tumors. In this review, we present the current landscape of bispecific antibodies for the treatment of lung cancer and discuss potential scenarios where the role of these therapeutics might expand in the near future.

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