Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer

Bispecific antibodies are a promising type of therapy for the treatment of cancer due to their ability to simultaneously inhibit different proteins playing a role in cancer progression. The development in lung cancer has been singularly intense because of the increasingly vast knowledge of the under...

Descripción completa

Detalles Bibliográficos
Autores principales: Arasanz, Hugo, Chocarro, Luisa, Fernández-Rubio, Leticia, Blanco, Ester, Bocanegra, Ana, Echaide, Miriam, Labiano, Ibone, Huerta, Ana Elsa, Alsina, Maria, Vera, Ruth, Escors, David, Kochan, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298459/
https://www.ncbi.nlm.nih.gov/pubmed/37373003
http://dx.doi.org/10.3390/ijms24129855
_version_ 1785064120548065280
author Arasanz, Hugo
Chocarro, Luisa
Fernández-Rubio, Leticia
Blanco, Ester
Bocanegra, Ana
Echaide, Miriam
Labiano, Ibone
Huerta, Ana Elsa
Alsina, Maria
Vera, Ruth
Escors, David
Kochan, Grazyna
author_facet Arasanz, Hugo
Chocarro, Luisa
Fernández-Rubio, Leticia
Blanco, Ester
Bocanegra, Ana
Echaide, Miriam
Labiano, Ibone
Huerta, Ana Elsa
Alsina, Maria
Vera, Ruth
Escors, David
Kochan, Grazyna
author_sort Arasanz, Hugo
collection PubMed
description Bispecific antibodies are a promising type of therapy for the treatment of cancer due to their ability to simultaneously inhibit different proteins playing a role in cancer progression. The development in lung cancer has been singularly intense because of the increasingly vast knowledge of the underlying molecular routes, in particular, in oncogene-driven tumors. In this review, we present the current landscape of bispecific antibodies for the treatment of lung cancer and discuss potential scenarios where the role of these therapeutics might expand in the near future.
format Online
Article
Text
id pubmed-10298459
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102984592023-06-28 Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer Arasanz, Hugo Chocarro, Luisa Fernández-Rubio, Leticia Blanco, Ester Bocanegra, Ana Echaide, Miriam Labiano, Ibone Huerta, Ana Elsa Alsina, Maria Vera, Ruth Escors, David Kochan, Grazyna Int J Mol Sci Review Bispecific antibodies are a promising type of therapy for the treatment of cancer due to their ability to simultaneously inhibit different proteins playing a role in cancer progression. The development in lung cancer has been singularly intense because of the increasingly vast knowledge of the underlying molecular routes, in particular, in oncogene-driven tumors. In this review, we present the current landscape of bispecific antibodies for the treatment of lung cancer and discuss potential scenarios where the role of these therapeutics might expand in the near future. MDPI 2023-06-07 /pmc/articles/PMC10298459/ /pubmed/37373003 http://dx.doi.org/10.3390/ijms24129855 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Arasanz, Hugo
Chocarro, Luisa
Fernández-Rubio, Leticia
Blanco, Ester
Bocanegra, Ana
Echaide, Miriam
Labiano, Ibone
Huerta, Ana Elsa
Alsina, Maria
Vera, Ruth
Escors, David
Kochan, Grazyna
Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title_full Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title_fullStr Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title_full_unstemmed Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title_short Current Indications and Future Landscape of Bispecific Antibodies for the Treatment of Lung Cancer
title_sort current indications and future landscape of bispecific antibodies for the treatment of lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298459/
https://www.ncbi.nlm.nih.gov/pubmed/37373003
http://dx.doi.org/10.3390/ijms24129855
work_keys_str_mv AT arasanzhugo currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT chocarroluisa currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT fernandezrubioleticia currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT blancoester currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT bocanegraana currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT echaidemiriam currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT labianoibone currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT huertaanaelsa currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT alsinamaria currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT veraruth currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT escorsdavid currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer
AT kochangrazyna currentindicationsandfuturelandscapeofbispecificantibodiesforthetreatmentoflungcancer

Ejemplares similares