Additional Genetic Alterations and Clonal Evolution of MPNs with Double Mutations on the MPL Gene: Two Case Reports

Essential thrombocythemia (ET) and primary myelofibrosis (PMF) are two of the main BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs) characterized by abnormal megakaryocytic proliferation. Janus kinase 2 (JAK2) mutations are detected in 50–60% of ET and PMF, while myeloproliferative leuk...

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Detalles Bibliográficos
Autores principales: Pennisi, Maria Stella, Di Gregorio, Sandra, Tirrò, Elena, Romano, Chiara, Duminuco, Andrea, Garibaldi, Bruno, Giuffrida, Gaetano, Manzella, Livia, Vigneri, Paolo, Palumbo, Giuseppe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298502/
https://www.ncbi.nlm.nih.gov/pubmed/37367082
http://dx.doi.org/10.3390/hematolrep15020033

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