Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides

Herein, we report the design and synthesis of novel 7-aza-coumarine-3-carboxamides via scaffold-hopping strategy and evaluation of their in vitro anticancer activity. Additionally, the improved non-catalytic synthesis of 7-azacoumarin-3-carboxylic acid is reported, which features water as the reacti...

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Detalles Bibliográficos
Autores principales: Trifonov, Alexey V., Gazizov, Almir S., Tapalova, Anipa S., Kibardina, Lyudmila K., Appazov, Nurbol O., Voloshina, Alexandra D., Sapunova, Anastasiia S., Luybina, Anna P., Abyzbekova, Gulmira M., Dobrynin, Alexey B., Litvinov, Igor A., Tauekel, Akerke K., Yespenbetova, Sholpan O., Burilov, Alexander R., Pudovik, Michail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298512/
https://www.ncbi.nlm.nih.gov/pubmed/37373075
http://dx.doi.org/10.3390/ijms24129927

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