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Synthesis and Anticancer Activity of A-Ring-Modified Derivatives of Dihydrobetulin

Multidrug resistance (MDR) is a common phenomenon in clinical oncology, whereby cancer cells become resistant to chemotherapeutic drugs. A common MDR mechanism is the overexpression of ATP-binding cassette efflux transporters in cancer cells, with P-glycoprotein (P-gp) being one of them. New 3,4-sec...

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Detalles Bibliográficos
Autores principales: Tolmacheva, Irina, Beloglazova, Yulia, Nazarov, Mikhail, Gagarskikh, Olga, Grishko, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298530/
https://www.ncbi.nlm.nih.gov/pubmed/37373011
http://dx.doi.org/10.3390/ijms24129863