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REST Targets JAK–STAT and HIF-1 Signaling Pathways in Human Down Syndrome Brain and Neural Cells

Down syndrome (DS) is the most frequently diagnosed chromosomal disorder of chromosome 21 (HSA21) aneuploidy, characterized by intellectual disability and reduced lifespan. The transcription repressor, Repressor Element-1 Silencing Transcription factor (REST), which acts as an epigenetic regulator,...

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Detalles Bibliográficos
Autores principales:	Huang, Tan, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298578/ https://www.ncbi.nlm.nih.gov/pubmed/37373133 http://dx.doi.org/10.3390/ijms24129980

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