Cargando…

QbD-Optimized, Phospholipid-Based Elastic Nanovesicles for the Effective Delivery of 6-Gingerol: A Promising Topical Option for Pain-Related Disorders

In this study, elastic nanovesicles, constructed of phospholipids optimized by Quality by Design (QbD), release 6-gingerol (6-G), a natural chemical that may alleviate osteoporosis and musculoskeletal-related pain. A 6-gingerol-loaded transfersome (6-GTF) formulation was developed using a thin film...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghazwani, Mohammed, Alqarni, Mohammed H., Hani, Umme, Alam, Aftab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298657/ https://www.ncbi.nlm.nih.gov/pubmed/37373129 http://dx.doi.org/10.3390/ijms24129983

Ejemplares similares

Quality-by-Design-Assisted Optimization of Carvacrol Oil-Loaded Niosomal Gel for Anti-Inflammatory Efficacy by Topical Route
por: Ghazwani, Mohammed, et al.
Publicado: (2023)

Beta Caryophyllene-Loaded Nanostructured Lipid Carriers for Topical Management of Skin Disorders: Statistical Optimization, In Vitro and Dermatokinetic Evaluation
por: Ghazwani, Mohammed, et al.
Publicado: (2023)

Development and Characterization of Methyl-Anthranilate-Loaded Silver Nanoparticles: A Phytocosmetic Sunscreen Gel for UV Protection
por: Ghazwani, Mohammed, et al.
Publicado: (2023)

Evaluations of Quality by Design (QbD) Elements Impact for Developing Niosomes as a Promising Topical Drug Delivery Platform
por: Shah, Parinbhai, et al.
Publicado: (2020)

A QbD Approach to Design and to Optimize the Self-Emulsifying Resveratrol–Phospholipid Complex to Enhance Drug Bioavailability through Lymphatic Transport
por: Gausuzzaman, Syed Abul Layes, et al.
Publicado: (2022)

Early Implementation of QbD in Biopharmaceutical Development: A Practical Example
por: Zurdo, Jesús, et al.
Publicado: (2015)

Pharmaceutical Development and Design of Thermosensitive Liposomes Based on the QbD Approach
por: Dobó, Dorina Gabriella, et al.
Publicado: (2022)

QbD Based Media Development for the Production of Fab Fragments in E. coli
por: Kumar, Deepak, et al.
Publicado: (2019)

QbD Enabled Azacitidine Loaded Liposomal Nanoformulation and Its In Vitro Evaluation
por: Kesharwani, Prashant, et al.
Publicado: (2021)

An Updated Risk Assessment as Part of the QbD-Based Liposome Design and Development
por: Németh, Zsófia, et al.
Publicado: (2021)

Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization
por: Aldawsari, Hibah M., et al.
Publicado: (2022)

Implementation of QbD strategies in the inoculum expansion of a mAb production process
por: Böhl, Ole Jacob, et al.
Publicado: (2020)

Toward QbD Process Understanding on DNA Vaccine Purification Using Design of Experiment
por: Hocharoen, Lalintip, et al.
Publicado: (2021)

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach
por: Almotairi, Nawaf, et al.
Publicado: (2022)

Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation
por: Donthi, Mahipal Reddy, et al.
Publicado: (2023)

Design Space and QbD Approach for Production of Drug Nanocrystals by Wet Media Milling Techniques
por: Peltonen, Leena
Publicado: (2018)

QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia
por: Kovács, Anita, et al.
Publicado: (2020)

Novel NIR modeling design and assignment in process quality control of Honeysuckle flower by QbD
por: Ma, Lijuan, et al.
Publicado: (2020)

Investigation of Silicone-Containing Semisolid in Situ Film-Forming Systems Using QbD Tools
por: Kis, Nikolett, et al.
Publicado: (2019)

Industrial application of QbD and NIR chemometric models in quality improvement of immediate release tablets
por: Ramadan, Ahmed, et al.
Publicado: (2021)

Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product
por: Pielenhofer, Jonas, et al.
Publicado: (2023)

Application of the Quality by Design Concept (QbD) in the Development of Hydrogel-Based Drug Delivery Systems
por: Mohseni-Motlagh, S. Farid, et al.
Publicado: (2023)

The way to a design space for an animal cell culture process according to Quality by Design (QbD)
por: Puskeiler, Robert, et al.
Publicado: (2011)

Application of QbD Principles for the Evaluation of Empty Hard Capsules as an Input Parameter in Formulation Development and Manufacturing
por: Stegemann, Sven, et al.
Publicado: (2014)

Development and Validation of a UPLC Method by the QbD-Approach for the Estimation of Rabeprazole and Levosulpiride from Capsules
por: Thummala, Veera Raghava Raju, et al.
Publicado: (2014)

Novel Phenobarbital-Loaded Nanostructured Lipid Carriers for Epilepsy Treatment: From QbD to In Vivo Evaluation
por: Scioli-Montoto, Sebastian, et al.
Publicado: (2022)

Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies
por: Wohlenberg, Ole Jacob, et al.
Publicado: (2022)

QbD driven targeted pulmonary delivery of dexamethasone-loaded chitosan microspheres: Biodistribution and pharmacokinetic study
por: Asha, B.R., et al.
Publicado: (2023)

Satisfying QTPP of Erythropoietin Biosimilar by QbD through DoE-Derived Downstream Process Engineering
por: Nag, Kakon, et al.
Publicado: (2023)

Quality by Design (QbD) Based Method for Estimation of Xanthohumol in Bulk and Solid Lipid Nanoparticles and Validation
por: Harish, Vancha, et al.
Publicado: (2023)

Hybrid modeling as a QbD/PAT tool in process development: an industrial E. coli case study
por: von Stosch, Moritz, et al.
Publicado: (2016)

QbD based approach for optimization of Tenofovir disoproxil fumarate loaded liquid crystal precursor with improved permeability
por: Patil, Sharvil, et al.
Publicado: (2017)

Development of Metronidazole Loaded Chitosan Nanoparticles Using QbD Approach—A Novel and Potential Antibacterial Formulation
por: Sreeharsha, Nagaraja, et al.
Publicado: (2020)

Fluidised bed granulation of two APIs: QbD approach and development of a NIR in-line monitoring method
por: Gavan, Alexandru, et al.
Publicado: (2020)

QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form
por: Palakurthi, Ashok K., et al.
Publicado: (2020)

Quality by design (QbD) approach in processing polymeric nanoparticles loading anticancer drugs by high pressure homogenizer
por: Soni, Govind, et al.
Publicado: (2020)

QbD Consideration for Developing a Double-Layered Tablet into a Single-Layered Tablet with Telmisartan and Amlodipine
por: Kim, Joo-Eun, et al.
Publicado: (2022)

Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies
por: Rizg, Waleed Y., et al.
Publicado: (2022)

The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect
por: Barbalata, Cristina-Ioana, et al.
Publicado: (2022)

A QbD Approach for Evaluating the Effect of Selective Laser Sintering Parameters on Printability and Properties of Solid Oral Forms
por: Gueche, Yanis A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4p85923hdhb2rfdo1p9d1pp0r8