Cargando…

Role of the Sodium-Dependent Organic Anion Transporter (SOAT/SLC10A6) in Physiology and Pathophysiology

The sodium-dependent organic anion transporter (SOAT, gene symbol SLC10A6) specifically transports 3′- and 17′-monosulfated steroid hormones, such as estrone sulfate and dehydroepiandrosterone sulfate, into specific target cells. These biologically inactive sulfo-conjugated steroids occur in high co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wannowius, Marie, Karakus, Emre, Aktürk, Zekeriya, Breuer, Janina, Geyer, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298714/ https://www.ncbi.nlm.nih.gov/pubmed/37373074 http://dx.doi.org/10.3390/ijms24129926

Ejemplares similares

Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6)
por: Karakus, Emre, et al.
Publicado: (2018)

Functional Analysis of Rare Genetic Variants in the Negative Regulator of Intracellular Calcium Signaling RCAS/SLC10A7
por: Wannowius, Marie, et al.
Publicado: (2021)

Role of the Steroid Sulfate Uptake Transporter Soat (Slc10a6) in Adipose Tissue and 3T3-L1 Adipocytes
por: Karakus, Emre, et al.
Publicado: (2022)

The orphan solute carrier SLC10A7 is a novel negative regulator of intracellular calcium signaling
por: Karakus, Emre, et al.
Publicado: (2020)

Physiological and Pathophysiological Relevance of the Anion Transporter Slc26a9 in Multiple Organs
por: Liu, Xuemei, et al.
Publicado: (2018)

Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT
por: Grosser, Gary, et al.
Publicado: (2021)

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
por: Gorecki, Matthias, et al.
Publicado: (2020)

Cellular Physiology and Pathophysiology of EAAT Anion Channels
por: Kovermann, Peter, et al.
Publicado: (2022)

SOAT1 methylation is associated with coronary heart disease
por: Abuzhalihan, Jialin, et al.
Publicado: (2019)

Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes
por: Schmidt, Stephanie, et al.
Publicado: (2015)

Efficacy of olmesartan amlodipine in Colombian hypertensive patients (soat study)
por: Buendia, Richard, et al.
Publicado: (2017)

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
por: Oni, Tobiloba E., et al.
Publicado: (2020)

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma
por: Whisenant, Thomas C., et al.
Publicado: (2022)

Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters
por: Gorbunov, Dmitry, et al.
Publicado: (2014)

SOAT1 missense variant in two cats with sebaceous gland dysplasia
por: Kiener, Sarah, et al.
Publicado: (2023)

Arylsulfonylamino-Benzanilides as Inhibitors of the Apical Sodium-Dependent Bile Salt Transporter (SLC10A2)
por: Liu, Hong-Tao, et al.
Publicado: (2013)

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)
por: Wang, Li, et al.
Publicado: (2013)

Introduction of Organic Anion Transporters (SLC22A) and a Regulatory Mechanism by Caveolins
por: Lee, Woon Kyu, et al.
Publicado: (2006)

Sequencing of the Canine Cytochrome P450 CYP2C41 Gene and Genotyping of Its Polymorphic Occurrence in 36 Dog Breeds
por: Karakus, Emre, et al.
Publicado: (2021)

SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?
por: Löhr, Mario, et al.
Publicado: (2022)

A pan-cancer analysis identifies SOAT1 as an immunological and prognostic biomarker
por: HUANG, YANGQING, et al.
Publicado: (2023)

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis
por: Zhu, Tingting, et al.
Publicado: (2021)

Impacts of the SOAT1 genetic variants and protein expression on HBV-related hepatocellular carcinoma
por: Chen, Yulong, et al.
Publicado: (2021)

Ferroptosis sensitization in glioma: exploring the regulatory mechanism of SOAT1 and its therapeutic implications
por: Sun, Shicheng, et al.
Publicado: (2023)

Transport Characteristics of CJMAED™ Homogeneous Anion Exchange Membranes in Sodium Chloride and Sodium Sulfate Solutions
por: Sarapulova, Veronika, et al.
Publicado: (2021)

Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
por: Tippett, David N, et al.
Publicado: (2023)

SAT-354 Characterization of Cell Death Induced by SOAT1 Inhibition in Adrenocortical Carcinoma Cells
por: Weigand, Isabel, et al.
Publicado: (2019)

Circ-Tulp4 promotes β-cell adaptation to lipotoxicity by regulating soat1 expression
por: Wu, Liting, et al.
Publicado: (2020)

Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer
por: Xu, Huanji, et al.
Publicado: (2021)

High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth
por: Wang, Zhihua, et al.
Publicado: (2022)

The Role of AKR1B10 in Physiology and Pathophysiology
por: Endo, Satoshi, et al.
Publicado: (2021)

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
por: Kunji, Edmund R.S., et al.
Publicado: (2020)

Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta
por: Chatuphonprasert, Waranya, et al.
Publicado: (2018)

Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases
por: Jaggi, Amteshwar Singh, et al.
Publicado: (2015)

Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology
por: Pearce, David, et al.
Publicado: (2022)

The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine
por: Xia, Weiliang, et al.
Publicado: (2013)

Identification of Soat1 as a Quantitative Trait Locus Gene on Mouse Chromosome 1 Contributing to Hyperlipidemia
por: Lu, Zongji, et al.
Publicado: (2011)

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis
por: Ren, Meiling, et al.
Publicado: (2021)

Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity
por: Harned, Taylor C., et al.
Publicado: (2023)

Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO(3)(-) transport and reduces survival in CFTR-deficient mice
por: Liu, Xuemei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m1otv85s6eule618tjc91f623q