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Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease

BACKGROUND: Formation of complexes between transglutaminase 2 (TG2) and gluten can mechanistically explain why TG2 serves both as B-cell autoantigen and as an enzyme that creates deamidated gluten epitopes in coeliac disease (CeD). A model has been proposed where TG2 released from shed epithelial ce...

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Detalles Bibliográficos
Autores principales:	Amundsen, Sunniva F., Stamnaes, Jorunn, Lundin, Knut E. A., Sollid, Ludvig M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298751/ https://www.ncbi.nlm.nih.gov/pubmed/37368893 http://dx.doi.org/10.1371/journal.pone.0287662

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