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A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction

(1) Study purpose: The aim of our prospective single-center, matched case–control study was to compare the number and volume of acute ischemic brain lesions following carotid endarterectomy (CEA) versus carotid artery stenting (CAS) using a propensity-matched design. (2) Methods: Carotid bifurcation...

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Autores principales: Mihály, Zsuzsanna, Booth, Samuel, Nguyen, Dat Tin, Vecsey-Nagy, Milán, Vértes, Miklós, Czinege, Zsófia, Péter, Csongor, Sótonyi, Péter, Varga, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298904/
https://www.ncbi.nlm.nih.gov/pubmed/37367422
http://dx.doi.org/10.3390/jcdd10060257
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author Mihály, Zsuzsanna
Booth, Samuel
Nguyen, Dat Tin
Vecsey-Nagy, Milán
Vértes, Miklós
Czinege, Zsófia
Péter, Csongor
Sótonyi, Péter
Varga, Andrea
author_facet Mihály, Zsuzsanna
Booth, Samuel
Nguyen, Dat Tin
Vecsey-Nagy, Milán
Vértes, Miklós
Czinege, Zsófia
Péter, Csongor
Sótonyi, Péter
Varga, Andrea
author_sort Mihály, Zsuzsanna
collection PubMed
description (1) Study purpose: The aim of our prospective single-center, matched case–control study was to compare the number and volume of acute ischemic brain lesions following carotid endarterectomy (CEA) versus carotid artery stenting (CAS) using a propensity-matched design. (2) Methods: Carotid bifurcation plaques were analyzed by using VascuCAP software on CT angiography (CTA) images. The number and volume of acute and chronic ischemic brain lesions were assessed on MRI scans taken 12–48 h after the procedures. Propensity score-based matching was performed at a 1:1 ratio to compare the ischemic lesions on postinterventional MR. (3) Results: A total of 107 patients (CAS, N = 33; CEA, N = 74) were included in the study. There were significant differences in smoking (p = 0.003), total calcification plaque volume (p = 0.004), and lengths of the lesion (p = 0.045) between the CAS and CEA groups. Propensity score matching resulted in 21 matched pairs of patients. Acute ischemic brain lesions were detected in ten patients (47.6%) of the matched CAS group and in three patients (14.2%) in the matched CEA group (p = 0.02). The volume of acute ischemic brain lesions was significantly larger (p = 0.04) in the CAS group than in the CEA group. New ischemic brain lesions were not associated with neurological symptoms in either group. (4) Conclusions: Procedure-related new acute ischemic brain lesions occurred significantly more frequently in the propensity-matched CAS group.
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spelling pubmed-102989042023-06-28 A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction Mihály, Zsuzsanna Booth, Samuel Nguyen, Dat Tin Vecsey-Nagy, Milán Vértes, Miklós Czinege, Zsófia Péter, Csongor Sótonyi, Péter Varga, Andrea J Cardiovasc Dev Dis Article (1) Study purpose: The aim of our prospective single-center, matched case–control study was to compare the number and volume of acute ischemic brain lesions following carotid endarterectomy (CEA) versus carotid artery stenting (CAS) using a propensity-matched design. (2) Methods: Carotid bifurcation plaques were analyzed by using VascuCAP software on CT angiography (CTA) images. The number and volume of acute and chronic ischemic brain lesions were assessed on MRI scans taken 12–48 h after the procedures. Propensity score-based matching was performed at a 1:1 ratio to compare the ischemic lesions on postinterventional MR. (3) Results: A total of 107 patients (CAS, N = 33; CEA, N = 74) were included in the study. There were significant differences in smoking (p = 0.003), total calcification plaque volume (p = 0.004), and lengths of the lesion (p = 0.045) between the CAS and CEA groups. Propensity score matching resulted in 21 matched pairs of patients. Acute ischemic brain lesions were detected in ten patients (47.6%) of the matched CAS group and in three patients (14.2%) in the matched CEA group (p = 0.02). The volume of acute ischemic brain lesions was significantly larger (p = 0.04) in the CAS group than in the CEA group. New ischemic brain lesions were not associated with neurological symptoms in either group. (4) Conclusions: Procedure-related new acute ischemic brain lesions occurred significantly more frequently in the propensity-matched CAS group. MDPI 2023-06-13 /pmc/articles/PMC10298904/ /pubmed/37367422 http://dx.doi.org/10.3390/jcdd10060257 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mihály, Zsuzsanna
Booth, Samuel
Nguyen, Dat Tin
Vecsey-Nagy, Milán
Vértes, Miklós
Czinege, Zsófia
Péter, Csongor
Sótonyi, Péter
Varga, Andrea
A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title_full A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title_fullStr A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title_full_unstemmed A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title_short A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction
title_sort propensity-matched comparison of ischemic brain lesions on postprocedural mri in endovascular versus open carotid artery reconstruction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298904/
https://www.ncbi.nlm.nih.gov/pubmed/37367422
http://dx.doi.org/10.3390/jcdd10060257
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