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Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation
Background and Objectives: The present study aims to provide prenatal 2-dimensional ultrasonographic (2D-US) nomograms of the normal cerebellar area. Materials and Methods: This is a prospective cross-sectional analysis of 252 normal singleton pregnancies, ranging from 13 to 39 weeks of gestation. T...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299055/ https://www.ncbi.nlm.nih.gov/pubmed/37373772 http://dx.doi.org/10.3390/jcm12124080 |
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author | Manzo, Luigi Orlandi, Giuliana Gabrielli, Olimpia Toscano, Paolo Di Lella, Enrica Lettieri, Antonia Mazzarelli, Laura Letizia Sica, Giordana Di Meglio, Letizia Di Meglio, Lavinia Ruffo, Gabriele Sica, Carmine Gulino, Ferdinando Antonio Incognito, Giosuè Giordano Tuscano, Attilio Giorno, Alice Di Meglio, Aniello |
author_facet | Manzo, Luigi Orlandi, Giuliana Gabrielli, Olimpia Toscano, Paolo Di Lella, Enrica Lettieri, Antonia Mazzarelli, Laura Letizia Sica, Giordana Di Meglio, Letizia Di Meglio, Lavinia Ruffo, Gabriele Sica, Carmine Gulino, Ferdinando Antonio Incognito, Giosuè Giordano Tuscano, Attilio Giorno, Alice Di Meglio, Aniello |
author_sort | Manzo, Luigi |
collection | PubMed |
description | Background and Objectives: The present study aims to provide prenatal 2-dimensional ultrasonographic (2D-US) nomograms of the normal cerebellar area. Materials and Methods: This is a prospective cross-sectional analysis of 252 normal singleton pregnancies, ranging from 13 to 39 weeks of gestation. The operator performed measurements of the fetal cerebellar area in the transverse plane using 2D-US. The relationship between cerebellar area and gestational age (GA) was determined through regression equations. Results: A significant, strong positive correlation was investigated between the cerebellar area with GA (r-value = 0.89), and a positive correlation indicates that with increasing GA, the cerebellar area increased in all the participants of the study. Several 2D-US nomograms of the normal cerebellar area were provided, and an increase of 0.4% in the cerebellar area each week of GA was reported. Conclusions: We presented information on the typical dimensions of the fetal cerebellar area throughout gestation. In future studies, it could be evaluated how the cerebellar area changes with cerebellar abnormalities. It should be established if calculating the cerebellar area in addition to the routine transverse cerebellar diameter may help in discriminating posterior fossa anomalies or even help to identify anomalies that would otherwise remain undetected. |
format | Online Article Text |
id | pubmed-10299055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102990552023-06-28 Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation Manzo, Luigi Orlandi, Giuliana Gabrielli, Olimpia Toscano, Paolo Di Lella, Enrica Lettieri, Antonia Mazzarelli, Laura Letizia Sica, Giordana Di Meglio, Letizia Di Meglio, Lavinia Ruffo, Gabriele Sica, Carmine Gulino, Ferdinando Antonio Incognito, Giosuè Giordano Tuscano, Attilio Giorno, Alice Di Meglio, Aniello J Clin Med Article Background and Objectives: The present study aims to provide prenatal 2-dimensional ultrasonographic (2D-US) nomograms of the normal cerebellar area. Materials and Methods: This is a prospective cross-sectional analysis of 252 normal singleton pregnancies, ranging from 13 to 39 weeks of gestation. The operator performed measurements of the fetal cerebellar area in the transverse plane using 2D-US. The relationship between cerebellar area and gestational age (GA) was determined through regression equations. Results: A significant, strong positive correlation was investigated between the cerebellar area with GA (r-value = 0.89), and a positive correlation indicates that with increasing GA, the cerebellar area increased in all the participants of the study. Several 2D-US nomograms of the normal cerebellar area were provided, and an increase of 0.4% in the cerebellar area each week of GA was reported. Conclusions: We presented information on the typical dimensions of the fetal cerebellar area throughout gestation. In future studies, it could be evaluated how the cerebellar area changes with cerebellar abnormalities. It should be established if calculating the cerebellar area in addition to the routine transverse cerebellar diameter may help in discriminating posterior fossa anomalies or even help to identify anomalies that would otherwise remain undetected. MDPI 2023-06-16 /pmc/articles/PMC10299055/ /pubmed/37373772 http://dx.doi.org/10.3390/jcm12124080 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Manzo, Luigi Orlandi, Giuliana Gabrielli, Olimpia Toscano, Paolo Di Lella, Enrica Lettieri, Antonia Mazzarelli, Laura Letizia Sica, Giordana Di Meglio, Letizia Di Meglio, Lavinia Ruffo, Gabriele Sica, Carmine Gulino, Ferdinando Antonio Incognito, Giosuè Giordano Tuscano, Attilio Giorno, Alice Di Meglio, Aniello Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title | Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title_full | Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title_fullStr | Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title_full_unstemmed | Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title_short | Fetal Cerebellar Area: Ultrasound Reference Ranges at 13–39 Weeks of Gestation |
title_sort | fetal cerebellar area: ultrasound reference ranges at 13–39 weeks of gestation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299055/ https://www.ncbi.nlm.nih.gov/pubmed/37373772 http://dx.doi.org/10.3390/jcm12124080 |
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