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Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings
The polylactic acid-glycolic acid copolymer (PLGA) has been proven to be applicable in medicine, but there is limited research on its application and safety in the agricultural field. In this paper, thifluzamide PLGA microspheres were prepared via phacoemulsification and solvent volatilization, usin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299088/ https://www.ncbi.nlm.nih.gov/pubmed/37373269 http://dx.doi.org/10.3390/ijms241210121 |
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author | Li, Yuanyuan Wang, Chaojie Deng, Xile Cai, Runze Cao, Lidong Cao, Chong Zheng, Li Zhao, Pengyue Huang, Qiliang |
author_facet | Li, Yuanyuan Wang, Chaojie Deng, Xile Cai, Runze Cao, Lidong Cao, Chong Zheng, Li Zhao, Pengyue Huang, Qiliang |
author_sort | Li, Yuanyuan |
collection | PubMed |
description | The polylactic acid-glycolic acid copolymer (PLGA) has been proven to be applicable in medicine, but there is limited research on its application and safety in the agricultural field. In this paper, thifluzamide PLGA microspheres were prepared via phacoemulsification and solvent volatilization, using the PLGA copolymer as the carrier and thifluzamide as the active component. It was found that the microspheres had good slow-release performance and fungicidal activity against Rhizoctonia solani. A comparative study was conducted to show the effect of thifluzamide PLGA microspheres on cucumber seedlings. Physiological and biochemical indexes of cucumber seedlings, including dry weight, root length, chlorophyll, protein, flavonoids, and total phenol content, indicated that the negative effect of thifluzamide on plant growth could be mitigated when it was wrapped in PLGA microspheres. This work explores the feasibility of PLGA as carriers in fungicide applications. |
format | Online Article Text |
id | pubmed-10299088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102990882023-06-28 Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings Li, Yuanyuan Wang, Chaojie Deng, Xile Cai, Runze Cao, Lidong Cao, Chong Zheng, Li Zhao, Pengyue Huang, Qiliang Int J Mol Sci Article The polylactic acid-glycolic acid copolymer (PLGA) has been proven to be applicable in medicine, but there is limited research on its application and safety in the agricultural field. In this paper, thifluzamide PLGA microspheres were prepared via phacoemulsification and solvent volatilization, using the PLGA copolymer as the carrier and thifluzamide as the active component. It was found that the microspheres had good slow-release performance and fungicidal activity against Rhizoctonia solani. A comparative study was conducted to show the effect of thifluzamide PLGA microspheres on cucumber seedlings. Physiological and biochemical indexes of cucumber seedlings, including dry weight, root length, chlorophyll, protein, flavonoids, and total phenol content, indicated that the negative effect of thifluzamide on plant growth could be mitigated when it was wrapped in PLGA microspheres. This work explores the feasibility of PLGA as carriers in fungicide applications. MDPI 2023-06-14 /pmc/articles/PMC10299088/ /pubmed/37373269 http://dx.doi.org/10.3390/ijms241210121 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Yuanyuan Wang, Chaojie Deng, Xile Cai, Runze Cao, Lidong Cao, Chong Zheng, Li Zhao, Pengyue Huang, Qiliang Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title | Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title_full | Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title_fullStr | Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title_full_unstemmed | Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title_short | Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings |
title_sort | preparation of thifluzamide polylactic acid glycolic acid copolymer microspheres and its effect on the growth of cucumber seedlings |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299088/ https://www.ncbi.nlm.nih.gov/pubmed/37373269 http://dx.doi.org/10.3390/ijms241210121 |
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