Cargando…
Molecular BCR::ABL1 Quantification and ABL1 Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study
Chronic myeloid leukemia (CML) is a well-characterized oncological disease in which virtually all patients possess a translocation (9;22) that generates the tyrosine kinase BCR::ABL1 protein. This translocation represents one of the milestones in molecular oncology in terms of both diagnostic and pr...
Autores principales: | Marin, Anelis Maria, Wosniaki, Denise Kusma, Sanchuki, Heloisa Bruna Soligo, Munhoz, Eduardo Cilião, Nardin, Jeanine Marie, Soares, Gabriela Silva, Espinace, Dhienifer Caroline, de Holanda Farias, João Samuel, Veroneze, Bruna, Becker, Luiz Felipe, Costa, Guilherme Lima, Beltrame, Olair Carlos, de Oliveira, Jaqueline Carvalho, Cambri, Geison, Zanette, Dalila Luciola, Aoki, Mateus Nóbrega |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299107/ https://www.ncbi.nlm.nih.gov/pubmed/37373266 http://dx.doi.org/10.3390/ijms241210118 |
Ejemplares similares
-
Circulating Cell-Free Nucleic Acids as Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer
por: Marin, Anelis Maria, et al.
Publicado: (2023) -
Essential properties and pitfalls of colorimetric Reverse Transcription Loop-mediated Isothermal Amplification as a point-of-care test for SARS-CoV-2 diagnosis
por: de Oliveira Coelho, Bruna, et al.
Publicado: (2021) -
Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I
por: Mian, Afsar Ali, et al.
Publicado: (2012) -
Targeting BCR-ABL(+) stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex
por: Chen, Min, et al.
Publicado: (2017) -
Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells
por: Kawakami, Shohei, et al.
Publicado: (2022)