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Morphological Characterization of Human Lung Cancer Organoids Cultured in Type I Collagen Hydrogels: A Histological Approach
The malignity of lung cancer is conditioned by the tumor microenvironment (TME), in which cancer-associated fibroblasts (CAFs) are relevant. In this work, we generated organoids by combining A549 cells with CAFs and normal fibroblasts (NF) isolated from adenocarcinoma tumors. We optimized the condit...
Autores principales: | Monleón-Guinot, Irene, Milian, Lara, Martínez-Vallejo, Patricia, Sancho-Tello, María, Llop-Miguel, Mauro, Galbis, José Marcelo, Cremades, Antonio, Carda, Carmen, Mata, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299156/ https://www.ncbi.nlm.nih.gov/pubmed/37373279 http://dx.doi.org/10.3390/ijms241210131 |
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