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Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines
Pancreatic cysts are becoming a popular diagnostic tool due to the increased availability of high-quality cross-sectional imaging. Pancreatic cystic lesions constitute closed, liquid-containing cavities, which are either neoplastic or non-neoplastic. While serous lesions often follow a benign course...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299166/ https://www.ncbi.nlm.nih.gov/pubmed/37373713 http://dx.doi.org/10.3390/jcm12124020 |
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author | Vlăduţ, Cătălina Bilous, Dana Ciocîrlan, Mihai |
author_facet | Vlăduţ, Cătălina Bilous, Dana Ciocîrlan, Mihai |
author_sort | Vlăduţ, Cătălina |
collection | PubMed |
description | Pancreatic cysts are becoming a popular diagnostic tool due to the increased availability of high-quality cross-sectional imaging. Pancreatic cystic lesions constitute closed, liquid-containing cavities, which are either neoplastic or non-neoplastic. While serous lesions often follow a benign course, mucinous lesions can hide carcinoma and, therefore, require different management. Moreover, all cysts should be considered mucinous until proven otherwise, thus limiting the errors in managing these entities. Due to the need for high contrast soft tissue imaging, magnetic resonance imaging represents an elective, non-invasive diagnostic tool. Endoscopic ultrasound (EUS) has started gaining more prominence with regard to the proper diagnosis and management of pancreatic cysts, offering quality information with minimal risks. Enabling both the acquisition of endoscopic images of the papilla and the endosonographic high-quality evaluation of septae, mural nodules along with the vascular patterns of the lesion contribute to a definitive diagnosis. Moreover, the possibility of obtaining cytological or histological samples could become mandatory in the foreseeable future, allowing for more precise molecular testing. Future research should focus on detecting methods to quickly diagnose high-grade dysplasia or early cancer for patients with pancreatic cysts, thus allowing time for appropriate treatment and avoiding surgical overtreatment or over surveillance in selected cases. |
format | Online Article Text |
id | pubmed-10299166 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102991662023-06-28 Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines Vlăduţ, Cătălina Bilous, Dana Ciocîrlan, Mihai J Clin Med Review Pancreatic cysts are becoming a popular diagnostic tool due to the increased availability of high-quality cross-sectional imaging. Pancreatic cystic lesions constitute closed, liquid-containing cavities, which are either neoplastic or non-neoplastic. While serous lesions often follow a benign course, mucinous lesions can hide carcinoma and, therefore, require different management. Moreover, all cysts should be considered mucinous until proven otherwise, thus limiting the errors in managing these entities. Due to the need for high contrast soft tissue imaging, magnetic resonance imaging represents an elective, non-invasive diagnostic tool. Endoscopic ultrasound (EUS) has started gaining more prominence with regard to the proper diagnosis and management of pancreatic cysts, offering quality information with minimal risks. Enabling both the acquisition of endoscopic images of the papilla and the endosonographic high-quality evaluation of septae, mural nodules along with the vascular patterns of the lesion contribute to a definitive diagnosis. Moreover, the possibility of obtaining cytological or histological samples could become mandatory in the foreseeable future, allowing for more precise molecular testing. Future research should focus on detecting methods to quickly diagnose high-grade dysplasia or early cancer for patients with pancreatic cysts, thus allowing time for appropriate treatment and avoiding surgical overtreatment or over surveillance in selected cases. MDPI 2023-06-13 /pmc/articles/PMC10299166/ /pubmed/37373713 http://dx.doi.org/10.3390/jcm12124020 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Vlăduţ, Cătălina Bilous, Dana Ciocîrlan, Mihai Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title | Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title_full | Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title_fullStr | Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title_full_unstemmed | Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title_short | Real-Life Management of Pancreatic Cysts: Simplified Review of Current Guidelines |
title_sort | real-life management of pancreatic cysts: simplified review of current guidelines |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299166/ https://www.ncbi.nlm.nih.gov/pubmed/37373713 http://dx.doi.org/10.3390/jcm12124020 |
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