Dexamethasone Inhibits Heparan Sulfate Biosynthetic System and Decreases Heparan Sulfate Content in Orthotopic Glioblastoma Tumors in Mice

Glioblastoma (GB) is an aggressive cancer with a high probability of recurrence, despite active chemoradiotherapy with temozolomide (TMZ) and dexamethasone (DXM). These systemic drugs affect the glycosylated components of brain tissue involved in GB development; however, their effects on heparan sul...

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Detalles Bibliográficos
Autores principales: Sokolov, Dmitry K., Shevelev, Oleg B., Khotskina, Anna S., Tsidulko, Alexandra Y., Strokotova, Anastasia V., Kazanskaya, Galina M., Volkov, Alexander M., Kliver, Evgenii E., Aidagulova, Svetlana V., Zavjalov, Evgenii L., Grigorieva, Elvira V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299293/
https://www.ncbi.nlm.nih.gov/pubmed/37373391
http://dx.doi.org/10.3390/ijms241210243

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