Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment

Biodegradable metal systems are the future of modern implantology. This publication describes the preparation of porous iron-based materials using a simple, affordable replica method on a polymeric template. We obtained two iron-based materials with different pore sizes for potential application in...

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Detalles Bibliográficos
Autores principales: Gąsior, Gabriela, Grodzicka, Marlena, Jędrzejewski, Tomasz, Wiśniewski, Marek, Radtke, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299352/
https://www.ncbi.nlm.nih.gov/pubmed/37367257
http://dx.doi.org/10.3390/jfb14060293
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author Gąsior, Gabriela
Grodzicka, Marlena
Jędrzejewski, Tomasz
Wiśniewski, Marek
Radtke, Aleksandra
author_facet Gąsior, Gabriela
Grodzicka, Marlena
Jędrzejewski, Tomasz
Wiśniewski, Marek
Radtke, Aleksandra
author_sort Gąsior, Gabriela
collection PubMed
description Biodegradable metal systems are the future of modern implantology. This publication describes the preparation of porous iron-based materials using a simple, affordable replica method on a polymeric template. We obtained two iron-based materials with different pore sizes for potential application in cardiac surgery implants. The materials were compared in terms of their corrosion rate (using immersion and electrochemical methods) and their cytotoxic activity (indirect test on three cell lines: mouse L929 fibroblasts, human aortic smooth muscle cells (HAMSC), and human umbilical vein endothelial cells (HUVEC)). Our research proved that the material being too porous might have a toxic effect on cell lines due to rapid corrosion.
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spelling pubmed-102993522023-06-28 Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment Gąsior, Gabriela Grodzicka, Marlena Jędrzejewski, Tomasz Wiśniewski, Marek Radtke, Aleksandra J Funct Biomater Article Biodegradable metal systems are the future of modern implantology. This publication describes the preparation of porous iron-based materials using a simple, affordable replica method on a polymeric template. We obtained two iron-based materials with different pore sizes for potential application in cardiac surgery implants. The materials were compared in terms of their corrosion rate (using immersion and electrochemical methods) and their cytotoxic activity (indirect test on three cell lines: mouse L929 fibroblasts, human aortic smooth muscle cells (HAMSC), and human umbilical vein endothelial cells (HUVEC)). Our research proved that the material being too porous might have a toxic effect on cell lines due to rapid corrosion. MDPI 2023-05-24 /pmc/articles/PMC10299352/ /pubmed/37367257 http://dx.doi.org/10.3390/jfb14060293 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gąsior, Gabriela
Grodzicka, Marlena
Jędrzejewski, Tomasz
Wiśniewski, Marek
Radtke, Aleksandra
Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title_full Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title_fullStr Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title_full_unstemmed Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title_short Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment
title_sort comparative study of porous iron foams for biodegradable implants: structural analysis and in vitro assessment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299352/
https://www.ncbi.nlm.nih.gov/pubmed/37367257
http://dx.doi.org/10.3390/jfb14060293
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