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Less Severe Lipopolysaccharide-Induced Inflammation in Conditional mgmt-Deleted Mice with LysM-Cre System: The Loss of DNA Repair in Macrophages

Despite the known influence of DNA methylation from lipopolysaccharide (LPS) activation, data on the O6-methylguanine-DNA methyltransferase (MGMT, a DNA suicide repair enzyme) in macrophages is still lacking. The transcriptomic profiling of epigenetic enzymes from wild-type macrophages after single...

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Detalles Bibliográficos
Autores principales: Saisorn, Wilasinee, Phuengmaung, Pornpimol, Issara-Amphorn, Jiraphorn, Makjaroen, Jiradej, Visitchanakun, Peerapat, Sae-khow, Kritsanawan, Boonmee, Atsadang, Benjaskulluecha, Salisa, Nita-Lazar, Aleksandra, Palaga, Tanapat, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299370/
https://www.ncbi.nlm.nih.gov/pubmed/37373287
http://dx.doi.org/10.3390/ijms241210139