Maintaining Genome Integrity: Protein Kinases and Phosphatases Orchestrate the Balancing Act of DNA Double-Strand Breaks Repair in Cancer

DNA double-strand breaks (DSBs) are the most lethal DNA damages which lead to severe genome instability. Phosphorylation is one of the most important protein post-translation modifications involved in DSBs repair regulation. Kinases and phosphatases play coordinating roles in DSB repair by phosphory...

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Detalles Bibliográficos
Autores principales: Qin, Sisi, Kitty, Ichiwa, Hao, Yalan, Zhao, Fei, Kim, Wootae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299397/
https://www.ncbi.nlm.nih.gov/pubmed/37373360
http://dx.doi.org/10.3390/ijms241210212

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