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A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells

Introducing or correcting disease-causing mutations through genome editing in human pluripotent stem cells (hPSCs) followed by tissue-specific differentiation provide sustainable models of multiorgan diseases, such as cystic fibrosis (CF). However, low editing efficiency resulting in extended cell c...

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Detalles Bibliográficos
Autores principales:	Cuevas-Ocaña, Sara, Yang, Jin Ye, Aushev, Magomet, Schlossmacher, George, Bear, Christine E., Hannan, Nicholas R. F., Perkins, Neil D., Rossant, Janet, Wong, Amy P., Gray, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299534/ https://www.ncbi.nlm.nih.gov/pubmed/37373413 http://dx.doi.org/10.3390/ijms241210266

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