Cargando…

Hif1α/Dhrs3a Pathway Participates in Lipid Droplet Accumulation via Retinol and Ppar-γ in Fish Hepatocytes

Excessive hepatic lipid accumulation is a common phenomenon in cultured fish; however, its underlying mechanisms are poorly understood. Lipid droplet (LD)-related proteins play vital roles in LD accumulation. Herein, using a zebrafish liver cell line (ZFL), we show that LD accumulation is accompanie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Jingjing, Du, Yihui, Wang, Binbin, Ji, Mengmeng, Li, Hongyan, Xia, Yun, Zhang, Kai, Li, Zhifei, Xie, Wenping, Gong, Wangbao, Yu, Ermeng, Wang, Guangjun, Xie, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299640/ https://www.ncbi.nlm.nih.gov/pubmed/37373386 http://dx.doi.org/10.3390/ijms241210236

Ejemplares similares

Prostaglandin 2α Promotes Autophagy and Mitochondrial Energy Production in Fish Hepatocytes
por: Tian, Jingjing, et al.
Publicado: (2022)

Dietary Betaine Attenuates High-Carbohydrate-Diet-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis in Mandarin Fish (Siniperca chuatsi)
por: Li, Hongyan, et al.
Publicado: (2023)

Role of nuclear pregnane X receptor in Cu-induced lipid metabolism and xenobiotic responses in largemouth bass (Micropterus salmoides)
por: Li, Hongyan, et al.
Publicado: (2022)

Epizootic ulcerative syndrome causes cutaneous dysbacteriosis in hybrid snakehead (Channa maculata♀ × Channa argus♂)
por: Li, Zhifei, et al.
Publicado: (2019)

Water Treatment Effect, Microbial Community Structure, and Metabolic Characteristics in a Field-Scale Aquaculture Wastewater Treatment System
por: Li, Zhifei, et al.
Publicado: (2020)

Effectiveness of agricultural waste in the enhancement of biological denitrification of aquaculture wastewater
por: Gao, Shuwei, et al.
Publicado: (2022)

Broad Bean (Vicia faba L.) Induces Intestinal Inflammation in Grass Carp (Ctenopharyngodon idellus C. et V) by Increasing Relative Abundances of Intestinal Gram-Negative and Flagellated Bacteria
por: Li, Zhifei, et al.
Publicado: (2018)

Artificial substrata increase pond farming density of grass carp (Ctenopharyngodon idella) by increasing the bacteria that participate in nitrogen and phosphorus cycles in pond water
por: Li, Zhifei, et al.
Publicado: (2019)

Geographical Origin Traceability of Procambarus clarkii Based on Mineral Elements and Stable Isotopes
por: Xia, Yun, et al.
Publicado: (2022)

Combined effects of dietary faba bean water extract and vitamin K3 on growth performance, textural quality, intestinal characteristics, oxidative and immune responses in grass carp
por: Li, Yichao, et al.
Publicado: (2023)

Effects of hydraulic retention time and influent nitrate concentration on solid-phase denitrification system using wheat husk as carbon source
por: Niu, Shuhui, et al.
Publicado: (2023)

Value-Added Carp Products: Multi-Class Evaluation of Crisp Grass Carp by Machine Learning-Based Analysis of Blood Indexes
por: Fu, Bing, et al.
Publicado: (2020)

Gene Expression Profiling of Grass Carp (Ctenopharyngodon idellus) and Crisp Grass Carp
por: Yu, Ermeng, et al.
Publicado: (2014)

Safety evaluation of four faba bean extracts used as dietary supplements in grass carp culture based on hematological indices, hepatopancreatic function and nutritional condition
por: Ma, Lingling, et al.
Publicado: (2020)

Key Factors Affecting the Flesh Flavor Quality and the Nutritional Value of Grass Carp in Four Culture Modes
por: Zhang, Junming, et al.
Publicado: (2021)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
por: Glazer, Robert I., et al.
Publicado: (2008)

Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes
por: Rogue, Alexandra, et al.
Publicado: (2011)

Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance
por: Ruiz, Alexis, et al.
Publicado: (2018)

Prognostic Impact of DHRS9 Overexpression in Pancreatic Cancer
por: Li, Huang-bao, et al.
Publicado: (2020)

Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster
por: Yang, Yingying, et al.
Publicado: (2016)

CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis
por: Dai, Xiyu, et al.
Publicado: (2023)

The complete mitochondrial genome of Shizothorax grahami (Cypriniformes: Cyprinidae)
por: Zheng, Zonglin, et al.
Publicado: (2016)

DHRS9 Is a Stable Marker of Human Regulatory Macrophages
por: Riquelme, Paloma, et al.
Publicado: (2017)

Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism
por: Liu, Jia, et al.
Publicado: (2022)

Comparative genome-wide methylation analysis reveals epigenetic regulation of muscle development in grass carp (Ctenopharyngodon idellus) fed with whole faba bean
por: Li, Yichao, et al.
Publicado: (2022)

DHRS7 is an immune-related prognostic biomarker of KIRC and pan-cancer
por: Tang, Sheng, et al.
Publicado: (2022)

Downregulation of DHRS9 expression in colorectal cancer tissues and its prognostic significance
por: Hu, Liang, et al.
Publicado: (2015)

DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma
por: Zhou, Y, et al.
Publicado: (2018)

DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma
por: Luo, Xiangjian, et al.
Publicado: (2019)

Are Mutations in the DHRS9 Gene Causally Linked to Epilepsy? A Case Report
por: Calì, Francesco, et al.
Publicado: (2020)

STAMBPL1 promotes the progression of lung adenocarcinoma by inhibiting DHRS2 expression
por: Yang, Xiang, et al.
Publicado: (2023)

Metformin Attenuates Cardiac Hypertrophy Via the HIF-1α/PPAR-γ Signaling Pathway in High-Fat Diet Rats
por: Liu, Yuansheng, et al.
Publicado: (2022)

Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis
por: Feng, Jiao, et al.
Publicado: (2020)

A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer
por: Seibert, Julia K, et al.
Publicado: (2015)

Auxiliary Diagnosis and Prognostic Value of Dehydrogenase/Reductase 2 (DHRS2) in Various Tumors
por: An, Zhongwu, et al.
Publicado: (2023)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

Textural quality, growth parameters and oxidative responses in Nile tilapia (Oreochromis niloticus) fed faba bean water extract diet
por: Li, Yichao, et al.
Publicado: (2022)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

AMPK-PPARγ-Cidec Axis Drives the Fasting-Induced Lipid Droplet Aggregation in the Liver of Obese Mice
por: Li, Hongqiang, et al.
Publicado: (2022)

Metformin promotes osteogenic differentiation and prevents hyperglycaemia-induced osteoporosis by suppressing PPARγ expression: Metformin prevents osteoporosis by suppressing PPARγ
por: Zheng, Lifeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6s32q9ubrkk4p4llkmtm7ordk1