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Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection

The use of OCT to monitor intravitreal treatment varies in clinical practice and is not always mandatory. The ALBATROS data collection aimed to clarify the impact of routinely implemented OCT on clinical outcomes and its impact on vision-related quality of life (VRQoL). Methods: An observational coh...

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Autores principales: Schuster, Alexander K., Wolfram, Christian, Hudde, Tobias, Klatt, Alexander, Schnegelsberg, Birthe, Midani-Oezkan, Heven, Ross, Mike, Ziemssen, Focke, Pfeiffer, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299675/
https://www.ncbi.nlm.nih.gov/pubmed/37373576
http://dx.doi.org/10.3390/jcm12123881
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author Schuster, Alexander K.
Wolfram, Christian
Hudde, Tobias
Klatt, Alexander
Schnegelsberg, Birthe
Midani-Oezkan, Heven
Ross, Mike
Ziemssen, Focke
Pfeiffer, Norbert
author_facet Schuster, Alexander K.
Wolfram, Christian
Hudde, Tobias
Klatt, Alexander
Schnegelsberg, Birthe
Midani-Oezkan, Heven
Ross, Mike
Ziemssen, Focke
Pfeiffer, Norbert
author_sort Schuster, Alexander K.
collection PubMed
description The use of OCT to monitor intravitreal treatment varies in clinical practice and is not always mandatory. The ALBATROS data collection aimed to clarify the impact of routinely implemented OCT on clinical outcomes and its impact on vision-related quality of life (VRQoL). Methods: An observational cohort study included patients with retinal diseases starting an intravitreal anti-vascular endothelial growth factor treatment in Germany. Treatment followed clinical practice except mandatory OCT examination during the 12-month observation period. VRQoL was assessed by NEI VFQ-25 and compared with respect to OCT examinations and number of intravitreal injections in the different diseases (nAMD, DME, BRVO, CRVO). Results: 1478 patients (74.5 ± 10.9 years, 54.9% female) were included in the analysis. Patients had neovascular AMD (65.2%), DME (18.4%), BRVO (9.5%), or CRVO (6.9%). 8.8 ± 2.6 OCT examinations and 6.1 ± 3.2 intravitreal injections were performed within 12 months. VRQoL differed between indications at baseline, with substantially lower values for neovascular AMD and CRVO. After twelve months, an increase in visual acuity and visual functional scale was observed for nAMD, DME, and BRVO, while in DME only, there was an association between number of OCT examinations and VRQoL. Conclusion: Intravitreal treatment was able to maintain VRQoL over twelve months in a real-world setting. Regular OCT examinations were associated with higher gain in VRQoL in DME patients after 12 months.
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spelling pubmed-102996752023-06-28 Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection Schuster, Alexander K. Wolfram, Christian Hudde, Tobias Klatt, Alexander Schnegelsberg, Birthe Midani-Oezkan, Heven Ross, Mike Ziemssen, Focke Pfeiffer, Norbert J Clin Med Article The use of OCT to monitor intravitreal treatment varies in clinical practice and is not always mandatory. The ALBATROS data collection aimed to clarify the impact of routinely implemented OCT on clinical outcomes and its impact on vision-related quality of life (VRQoL). Methods: An observational cohort study included patients with retinal diseases starting an intravitreal anti-vascular endothelial growth factor treatment in Germany. Treatment followed clinical practice except mandatory OCT examination during the 12-month observation period. VRQoL was assessed by NEI VFQ-25 and compared with respect to OCT examinations and number of intravitreal injections in the different diseases (nAMD, DME, BRVO, CRVO). Results: 1478 patients (74.5 ± 10.9 years, 54.9% female) were included in the analysis. Patients had neovascular AMD (65.2%), DME (18.4%), BRVO (9.5%), or CRVO (6.9%). 8.8 ± 2.6 OCT examinations and 6.1 ± 3.2 intravitreal injections were performed within 12 months. VRQoL differed between indications at baseline, with substantially lower values for neovascular AMD and CRVO. After twelve months, an increase in visual acuity and visual functional scale was observed for nAMD, DME, and BRVO, while in DME only, there was an association between number of OCT examinations and VRQoL. Conclusion: Intravitreal treatment was able to maintain VRQoL over twelve months in a real-world setting. Regular OCT examinations were associated with higher gain in VRQoL in DME patients after 12 months. MDPI 2023-06-07 /pmc/articles/PMC10299675/ /pubmed/37373576 http://dx.doi.org/10.3390/jcm12123881 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Schuster, Alexander K.
Wolfram, Christian
Hudde, Tobias
Klatt, Alexander
Schnegelsberg, Birthe
Midani-Oezkan, Heven
Ross, Mike
Ziemssen, Focke
Pfeiffer, Norbert
Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title_full Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title_fullStr Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title_full_unstemmed Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title_short Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases—Results from the ALBATROS Data Collection
title_sort impact of routinely performed optical coherence tomography examinations on quality of life in patients with retinal diseases—results from the albatros data collection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299675/
https://www.ncbi.nlm.nih.gov/pubmed/37373576
http://dx.doi.org/10.3390/jcm12123881
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