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RANK(+)TLR2(+) myeloid subpopulation converts autoimmune to joint destruction in rheumatoid arthritis

Joint destruction is the major clinic burden in patients with rheumatoid arthritis (RA). It is unclear, though, how this autoimmune disease progresses to the point of deterioration of the joint. Here, we report that in a mouse model of RA the upregulation of TLR2 expression and its α(2,3) sialylatio...

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Detalles Bibliográficos
Autores principales: Zhang, Weixin, Noller, Kathleen, Crane, Janet, Wan, Mei, Wu, Xiaojun, Cahan, Patrick, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299822/
https://www.ncbi.nlm.nih.gov/pubmed/37204303
http://dx.doi.org/10.7554/eLife.85553

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