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RANK(+)TLR2(+) myeloid subpopulation converts autoimmune to joint destruction in rheumatoid arthritis
Joint destruction is the major clinic burden in patients with rheumatoid arthritis (RA). It is unclear, though, how this autoimmune disease progresses to the point of deterioration of the joint. Here, we report that in a mouse model of RA the upregulation of TLR2 expression and its α(2,3) sialylatio...
Autores principales: | Zhang, Weixin, Noller, Kathleen, Crane, Janet, Wan, Mei, Wu, Xiaojun, Cahan, Patrick, Cao, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299822/ https://www.ncbi.nlm.nih.gov/pubmed/37204303 http://dx.doi.org/10.7554/eLife.85553 |
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