Nonmonotone invasion landscape by noise-aware control of metastasis activator levels

A major pharmacological assumption is that lowering disease-promoting protein levels is generally beneficial. For example, inhibiting metastasis activator BACH1 is proposed to decrease cancer metastases. Testing such assumptions requires approaches to measure disease phenotypes while precisely adjus...

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Detalles Bibliográficos
Autores principales: Wan, Yiming, Cohen, Joseph, Szenk, Mariola, Farquhar, Kevin S., Coraci, Damiano, Krzysztoń, Rafał, Azukas, Joshua, Van Nest, Nicholas, Smashnov, Alex, Chern, Yi-Jye, De Martino, Daniela, Nguyen, Long Chi, Bien, Harold, Bravo-Cordero, Jose Javier, Chan, Chia-Hsin, Rosner, Marsha Rich, Balázsi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299915/
https://www.ncbi.nlm.nih.gov/pubmed/37231268
http://dx.doi.org/10.1038/s41589-023-01344-z

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