Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner

Genetic compensation responses (GCRs) can be induced by deleterious mutations in living organisms in order to maintain genetic robustness. One type of GCRs, homology-dependent GCR (HDGCR), involves transcriptional activation of one or more homologous genes related to the mutated gene. In zebrafish,...

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Detalles Bibliográficos
Autores principales: Xie, Aixuan, Ma, Zhipeng, Wang, Jinyang, Zhang, Yuxi, Chen, Yayue, Yang, Chun, Chen, Jun, Peng, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300044/
https://www.ncbi.nlm.nih.gov/pubmed/37369707
http://dx.doi.org/10.1038/s41421-023-00550-2

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