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Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China

Air pollution remains a major threat to cardiovascular health and most acute myocardial infarction (AMI) deaths occur at home. However, currently established knowledge on the deleterious effect of air pollution on AMI has been limited to routinely monitored air pollutants and overlooked the place of...

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Autores principales: Cheng, Jian, Zheng, Hao, Wei, Jing, Huang, Cunrui, Ho, Hung Chak, Sun, Shengzhi, Phung, Dung, Kim, Ho, Wang, Xiling, Bai, Zhongliang, Hossain, Mohammad Zahid, Tong, Shilu, Su, Hong, Xu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300167/
https://www.ncbi.nlm.nih.gov/pubmed/37247141
http://dx.doi.org/10.1007/s11356-023-27813-5
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author Cheng, Jian
Zheng, Hao
Wei, Jing
Huang, Cunrui
Ho, Hung Chak
Sun, Shengzhi
Phung, Dung
Kim, Ho
Wang, Xiling
Bai, Zhongliang
Hossain, Mohammad Zahid
Tong, Shilu
Su, Hong
Xu, Zhiwei
author_facet Cheng, Jian
Zheng, Hao
Wei, Jing
Huang, Cunrui
Ho, Hung Chak
Sun, Shengzhi
Phung, Dung
Kim, Ho
Wang, Xiling
Bai, Zhongliang
Hossain, Mohammad Zahid
Tong, Shilu
Su, Hong
Xu, Zhiwei
author_sort Cheng, Jian
collection PubMed
description Air pollution remains a major threat to cardiovascular health and most acute myocardial infarction (AMI) deaths occur at home. However, currently established knowledge on the deleterious effect of air pollution on AMI has been limited to routinely monitored air pollutants and overlooked the place of death. In this study, we examined the association between short-term residential exposure to China’s routinely monitored and unmonitored air pollutants and the risk of AMI deaths at home. A time-stratified case-crossover analysis was undertaken to associate short-term residential exposure to air pollution with 0.1 million AMI deaths at home in Jiangsu Province (China) during 2016–2019. Individual-level residential exposure to five unmonitored and monitored air pollutants including PM(1) (particulate matter with an aerodynamic diameter ≤ 1 μm) and PM(2.5) (particulate matter with an aerodynamic diameter ≤ 2.5 μm), SO(2) (sulfur dioxide), NO(2) (nitrogen dioxide), and O(3) (ozone) was estimated from satellite remote sensing and machine learning technique. We found that exposure to five air pollutants, even below the recently released stricter air quality standards of the World Health Organization (WHO), was all associated with increased odds of AMI deaths at home. The odds of AMI deaths increased by 20% (95% confidence interval: 8 to 33%), 22% (12 to 33%), 14% (2 to 27%), 13% (3 to 25%), and 7% (3 to 12%) for an interquartile range increase in PM(1), PM(2.5), SO(2), NO(2), and O(3), respectively. A greater magnitude of association between NO(2) or O(3) and AMI deaths was observed in females and in the warm season. The greatest association between PM(1) and AMI deaths was found in individuals aged ≤ 64 years. This study for the first time suggests that residential exposure to routinely monitored and unmonitored air pollutants, even below the newest WHO air quality standards, is still associated with higher odds of AMI deaths at home. Future studies are warranted to understand the biological mechanisms behind the triggering of AMI deaths by air pollution exposure, to develop intervention strategies to reduce AMI deaths triggered by air pollution exposure, and to evaluate the cost-effectiveness, accessibility, and sustainability of these intervention strategies. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11356-023-27813-5.
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spelling pubmed-103001672023-06-29 Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China Cheng, Jian Zheng, Hao Wei, Jing Huang, Cunrui Ho, Hung Chak Sun, Shengzhi Phung, Dung Kim, Ho Wang, Xiling Bai, Zhongliang Hossain, Mohammad Zahid Tong, Shilu Su, Hong Xu, Zhiwei Environ Sci Pollut Res Int Research Article Air pollution remains a major threat to cardiovascular health and most acute myocardial infarction (AMI) deaths occur at home. However, currently established knowledge on the deleterious effect of air pollution on AMI has been limited to routinely monitored air pollutants and overlooked the place of death. In this study, we examined the association between short-term residential exposure to China’s routinely monitored and unmonitored air pollutants and the risk of AMI deaths at home. A time-stratified case-crossover analysis was undertaken to associate short-term residential exposure to air pollution with 0.1 million AMI deaths at home in Jiangsu Province (China) during 2016–2019. Individual-level residential exposure to five unmonitored and monitored air pollutants including PM(1) (particulate matter with an aerodynamic diameter ≤ 1 μm) and PM(2.5) (particulate matter with an aerodynamic diameter ≤ 2.5 μm), SO(2) (sulfur dioxide), NO(2) (nitrogen dioxide), and O(3) (ozone) was estimated from satellite remote sensing and machine learning technique. We found that exposure to five air pollutants, even below the recently released stricter air quality standards of the World Health Organization (WHO), was all associated with increased odds of AMI deaths at home. The odds of AMI deaths increased by 20% (95% confidence interval: 8 to 33%), 22% (12 to 33%), 14% (2 to 27%), 13% (3 to 25%), and 7% (3 to 12%) for an interquartile range increase in PM(1), PM(2.5), SO(2), NO(2), and O(3), respectively. A greater magnitude of association between NO(2) or O(3) and AMI deaths was observed in females and in the warm season. The greatest association between PM(1) and AMI deaths was found in individuals aged ≤ 64 years. This study for the first time suggests that residential exposure to routinely monitored and unmonitored air pollutants, even below the newest WHO air quality standards, is still associated with higher odds of AMI deaths at home. Future studies are warranted to understand the biological mechanisms behind the triggering of AMI deaths by air pollution exposure, to develop intervention strategies to reduce AMI deaths triggered by air pollution exposure, and to evaluate the cost-effectiveness, accessibility, and sustainability of these intervention strategies. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11356-023-27813-5. Springer Berlin Heidelberg 2023-05-29 2023 /pmc/articles/PMC10300167/ /pubmed/37247141 http://dx.doi.org/10.1007/s11356-023-27813-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Cheng, Jian
Zheng, Hao
Wei, Jing
Huang, Cunrui
Ho, Hung Chak
Sun, Shengzhi
Phung, Dung
Kim, Ho
Wang, Xiling
Bai, Zhongliang
Hossain, Mohammad Zahid
Tong, Shilu
Su, Hong
Xu, Zhiwei
Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title_full Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title_fullStr Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title_full_unstemmed Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title_short Short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in China
title_sort short-term residential exposure to air pollution and risk of acute myocardial infarction deaths at home in china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300167/
https://www.ncbi.nlm.nih.gov/pubmed/37247141
http://dx.doi.org/10.1007/s11356-023-27813-5
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