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Plexin D1 mediates disturbed flow-induced M1 macrophage polarization in atherosclerosis

Atherosclerosis preferentially develops at bifurcations exposed to disturbed flow. Plexin D1 (PLXND1) responds to mechanical forces and drives macrophage accumulation in atherosclerosis. Here, multiple strategies were used to identify the role of PLXND1 in site-specific atherosclerosis. Using comput...

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Detalles Bibliográficos
Autores principales: Zhang, Suhui, Zhang, Yingqian, Zhang, Peng, Wei, Zechen, Ma, Mingrui, Wang, Wei, Tong, Wei, Tian, Feng, Hui, Hui, Tian, Jie, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300222/
https://www.ncbi.nlm.nih.gov/pubmed/37389065
http://dx.doi.org/10.1016/j.heliyon.2023.e17314