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Plexin D1 mediates disturbed flow-induced M1 macrophage polarization in atherosclerosis
Atherosclerosis preferentially develops at bifurcations exposed to disturbed flow. Plexin D1 (PLXND1) responds to mechanical forces and drives macrophage accumulation in atherosclerosis. Here, multiple strategies were used to identify the role of PLXND1 in site-specific atherosclerosis. Using comput...
Autores principales: | Zhang, Suhui, Zhang, Yingqian, Zhang, Peng, Wei, Zechen, Ma, Mingrui, Wang, Wei, Tong, Wei, Tian, Feng, Hui, Hui, Tian, Jie, Chen, Yundai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300222/ https://www.ncbi.nlm.nih.gov/pubmed/37389065 http://dx.doi.org/10.1016/j.heliyon.2023.e17314 |
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