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A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis

Autoimmune pancreatitis (AIP) is an inflammatory condition of the pancreas, commonly characterized by elevated levels of immunoglobulin G (IgG) 4. Diagnosis of this condition can be challenging in patients with risk factors for other pancreatitis etiologies and requires a comprehensive approach util...

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Autores principales: Creech, Zachary A, Shastri, Divya, Hussain, Mohammed Wajid, Ikram, Waleed, MacElwee, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300237/
https://www.ncbi.nlm.nih.gov/pubmed/37388613
http://dx.doi.org/10.7759/cureus.39616
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author Creech, Zachary A
Shastri, Divya
Hussain, Mohammed Wajid
Ikram, Waleed
MacElwee, Mark
author_facet Creech, Zachary A
Shastri, Divya
Hussain, Mohammed Wajid
Ikram, Waleed
MacElwee, Mark
author_sort Creech, Zachary A
collection PubMed
description Autoimmune pancreatitis (AIP) is an inflammatory condition of the pancreas, commonly characterized by elevated levels of immunoglobulin G (IgG) 4. Diagnosis of this condition can be challenging in patients with risk factors for other pancreatitis etiologies and requires a comprehensive approach utilizing clinical, radiologic, and laboratory findings. Here, we present a case of an individual with a history of multiple prior hospitalizations for alcoholic pancreatitis, who presented with symptoms of abdominal pain, nausea, and vomiting. Computed tomography (CT) imaging revealed intra-abdominal abscesses and findings consistent with pancreatitis. Further laboratory results revealed elevated lipase and IgG4 levels, indicating AIP as the underlying cause. This case highlights the importance of considering AIP as a differential diagnosis in individuals presenting with pancreatic disease.
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spelling pubmed-103002372023-06-29 A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis Creech, Zachary A Shastri, Divya Hussain, Mohammed Wajid Ikram, Waleed MacElwee, Mark Cureus Endocrinology/Diabetes/Metabolism Autoimmune pancreatitis (AIP) is an inflammatory condition of the pancreas, commonly characterized by elevated levels of immunoglobulin G (IgG) 4. Diagnosis of this condition can be challenging in patients with risk factors for other pancreatitis etiologies and requires a comprehensive approach utilizing clinical, radiologic, and laboratory findings. Here, we present a case of an individual with a history of multiple prior hospitalizations for alcoholic pancreatitis, who presented with symptoms of abdominal pain, nausea, and vomiting. Computed tomography (CT) imaging revealed intra-abdominal abscesses and findings consistent with pancreatitis. Further laboratory results revealed elevated lipase and IgG4 levels, indicating AIP as the underlying cause. This case highlights the importance of considering AIP as a differential diagnosis in individuals presenting with pancreatic disease. Cureus 2023-05-28 /pmc/articles/PMC10300237/ /pubmed/37388613 http://dx.doi.org/10.7759/cureus.39616 Text en Copyright © 2023, Creech et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Creech, Zachary A
Shastri, Divya
Hussain, Mohammed Wajid
Ikram, Waleed
MacElwee, Mark
A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title_full A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title_fullStr A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title_full_unstemmed A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title_short A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
title_sort case of autoimmune pancreatitis presenting as alcohol-induced necrotizing pancreatitis
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300237/
https://www.ncbi.nlm.nih.gov/pubmed/37388613
http://dx.doi.org/10.7759/cureus.39616
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