Disruption of CDK7 signaling leads to catastrophic chromosomal instability coupled with a loss of condensin-mediated chromatin compaction

Chromatin organization is highly dynamic and modulates DNA replication, transcription, and chromosome segregation. Condensin is essential for chromosome assembly during mitosis and meiosis, as well as maintenance of chromosome structure during interphase. While it is well established that sustained...

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Detalles Bibliográficos
Autores principales: Piemonte, Katrina M., Webb, Bryan M., Bobbitt, Jessica R., Majmudar, Parth R., Cuellar-Vite, Leslie, Bryson, Benjamin L., Latina, Nicholas C., Seachrist, Darcie D., Keri, Ruth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300262/
https://www.ncbi.nlm.nih.gov/pubmed/37201585
http://dx.doi.org/10.1016/j.jbc.2023.104834

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