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Cry1 expression during postnatal development is critical for the establishment of normal circadian period

The mammalian circadian system generates an approximate 24-h rhythm through a complex autoregulatory feedback loop. Four genes, Period1 (Per1), Period2 (Per2), Cryptochrome1 (Cry1), and Cryptochrome2 (Cry2), regulate the negative feedback within this loop. Although these proteins have distinct roles...

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Detalles Bibliográficos
Autores principales: Schirmer, Aaron E., Kumar, Vivek, Schook, Andrew, Song, Eun Joo, Marshall, Michael S., Takahashi, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300422/
https://www.ncbi.nlm.nih.gov/pubmed/37389366
http://dx.doi.org/10.3389/fnins.2023.1166137