Memory B cell development elicited by mRNA booster vaccinations in the elderly

Despite mRNA vaccination, elderly individuals remain especially vulnerable to severe consequences of SARS-CoV-2 infection. Here, we compare the memory B cell responses in a cohort of elderly and younger individuals who received mRNA booster vaccinations. Plasma neutralizing potency and breadth were...

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Detalles Bibliográficos
Autores principales: Wang, Zijun, Muecksch, Frauke, Raspe, Raphael, Johannsen, Frederik, Turroja, Martina, Canis, Marie, ElTanbouly, Mohamed A., Santos, Gabriela S. Silva, Johnson, Brianna, Baharani, Viren A., Patejak, Rachel, Yao, Kai-Hui, Chirco, Bennett J., Millard, Katrina G., Shimeliovich, Irina, Gazumyan, Anna, Oliveira, Thiago Y., Bieniasz, Paul D., Hatziioannou, Theodora, Caskey, Marina, Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300432/
https://www.ncbi.nlm.nih.gov/pubmed/37368240
http://dx.doi.org/10.1084/jem.20230668

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