Cargando…

Skipper analysis of eCLIP datasets enables sensitive detection of constrained translation factor binding sites

Technology for crosslinking and immunoprecipitation (CLIP) followed by sequencing (CLIP-seq) has identified the transcriptomic targets of hundreds of RNA-binding proteins in cells. To increase the power of existing and future CLIP-seq datasets, we introduce Skipper, an end-to-end workflow that conve...

Descripción completa

Detalles Bibliográficos
Autores principales: Boyle, Evan A., Her, Hsuan-Lin, Mueller, Jasmine R., Naritomi, Jack T., Nguyen, Grady G., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300551/
https://www.ncbi.nlm.nih.gov/pubmed/37388912
http://dx.doi.org/10.1016/j.xgen.2023.100317