Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis

Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis characterized by enthesitis of the spine and sacroiliac joints. Genome-wide association studies (GWASs) have revealed more than 100 genetic associations whose functional effects remain largely unresolved. Here, we prese...

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Detalles Bibliográficos
Autores principales: Brown, Andrew C., Cohen, Carla J., Mielczarek, Olga, Migliorini, Gabriele, Costantino, Félicie, Allcock, Alice, Davidson, Connor, Elliott, Katherine S., Fang, Hai, Lledó Lara, Alicia, Martin, Alice C., Osgood, Julie A., Sanniti, Anna, Scozzafava, Giuseppe, Vecellio, Matteo, Zhang, Ping, Black, Mary Helen, Li, Shuwei, Truong, Dongnhu, Molineros, Julio, Howe, Trevor, Wordsworth, B. Paul, Bowness, Paul, Knight, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300554/
https://www.ncbi.nlm.nih.gov/pubmed/37388915
http://dx.doi.org/10.1016/j.xgen.2023.100306

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