ITGAL as a prognostic biomarker correlated with immune infiltrates in melanoma

This study investigates the relationship between ITGAL expression and immune infiltration, clinical prognosis, and specific types of T cells in melanoma tissue. The findings reveal the key role of ITGAL in melanoma and its potential mechanism of regulating tumor immune infiltrating cells, highlighti...

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Detalles Bibliográficos
Autores principales: Deng, TengFei, Wang, Chaoyong, Gao, Cong, Zhang, Qiang, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300562/
https://www.ncbi.nlm.nih.gov/pubmed/37388230
http://dx.doi.org/10.3389/fonc.2023.1181537
Descripción
Sumario:This study investigates the relationship between ITGAL expression and immune infiltration, clinical prognosis, and specific types of T cells in melanoma tissue. The findings reveal the key role of ITGAL in melanoma and its potential mechanism of regulating tumor immune infiltrating cells, highlighting its potential as a diagnostic biomarker and therapeutic target for advanced melanoma.

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