The spatio-temporal relationship between concurrent lesion and brain atrophy changes in early multiple sclerosis: A post-hoc analysis of the REFLEXION study

BACKGROUND: White matter (WM) lesions and brain atrophy are present early in multiple sclerosis (MS). However, their spatio-temporal relationship remains unclear. METHODS: Yearly magnetic resonance images were analysed in 387 patients with a first clinical demyelinating event (FCDE) from the 5-year...

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Detalles Bibliográficos
Autores principales: Gentile, Giordano, Mattiesing, Rozemarijn M., Brouwer, Iman, van Schijndel, Ronald A., Uitdehaag, Bernard M.J., Twisk, Jos W.R., Kappos, Ludwig, Freedman, Mark S., Comi, Giancarlo, Jack, Dominic, Barkhof, Frederik, De Stefano, Nicola, Vrenken, Hugo, Battaglini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300577/
https://www.ncbi.nlm.nih.gov/pubmed/37086648
http://dx.doi.org/10.1016/j.nicl.2023.103397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300577/
https://www.ncbi.nlm.nih.gov/pubmed/37086648
http://dx.doi.org/10.1016/j.nicl.2023.103397

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