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A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues
Background: Opioids are considered the cornerstone of pain management: they show good efficacy as a first-line therapy for moderate to severe cancer pain. Since pharmacokinetic/pharmacodynamic information about the tissue-specific effect and toxicity of opioids is still scarce, their quantification...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300969/ https://www.ncbi.nlm.nih.gov/pubmed/37375850 http://dx.doi.org/10.3390/ph16060903 |