A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues

Background: Opioids are considered the cornerstone of pain management: they show good efficacy as a first-line therapy for moderate to severe cancer pain. Since pharmacokinetic/pharmacodynamic information about the tissue-specific effect and toxicity of opioids is still scarce, their quantification...

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Detalles Bibliográficos
Autores principales: Manca, Alessandra, De Nicolò, Amedeo, De Vivo, Elisa Delia, Ferrara, Micol, Oh, Sharon, Khalili, Sahar, Higgins, Niamh, Deiss, Robert G., Bonora, Stefano, Cusato, Jessica, Palermiti, Alice, Mula, Jacopo, Gianella, Sara, D’Avolio, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300969/
https://www.ncbi.nlm.nih.gov/pubmed/37375850
http://dx.doi.org/10.3390/ph16060903

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