Cargando…

Novel Potential Janus Kinase Inhibitors with Therapeutic Prospects in Rheumatoid Arthritis Addressed by In Silico Studies

Rheumatoid arthritis (RA) is a debilitating autoimmune disorder with an inflammatory condition targeting the joints that affects millions of patients worldwide. Several unmet needs still need to be addressed despite recent improvements in the management of RA. Although current RA therapies can dimin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radu, Andrei-Flavius, Bungau, Simona Gabriela, Negru, Andrei Paul, Uivaraseanu, Bogdan, Bogdan, Mihaela Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300981/ https://www.ncbi.nlm.nih.gov/pubmed/37375255 http://dx.doi.org/10.3390/molecules28124699

Ejemplares similares

Simulation-Based Research on Phytoconstituents of Embelia ribes Targeting Proteins with Pathophysiological Implications in Rheumatoid Arthritis
por: Radu, Andrei-Flavius, et al.
Publicado: (2023)

Management of Rheumatoid Arthritis: An Overview
por: Radu, Andrei-Flavius, et al.
Publicado: (2021)

Application of Robotic Recovery Techniques to Stroke Survivors—Bibliometric Analysis
por: Uivarosan, Diana, et al.
Publicado: (2022)

Highlighting the Benefits of Rehabilitation Treatments in Hip Osteoarthritis
por: Radu, Andrei-Flavius, et al.
Publicado: (2022)

Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir
por: Negru, Paul Andrei, et al.
Publicado: (2022)

Exploring New Therapeutic Avenues for Ophthalmic Disorders: Glaucoma-Related Molecular Docking Evaluation and Bibliometric Analysis for Improved Management of Ocular Diseases
por: Bodea, Flaviu, et al.
Publicado: (2023)

An Evidence-Based Update on the Potential Association between Rheumatoid Arthritis and Lymphangioleiomyomatosis
por: Pascalau, Nicoleta Anamaria, et al.
Publicado: (2023)

The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications
por: Nistor-Cseppento, Carmen Delia, et al.
Publicado: (2022)

Characterization of the Toxicological Impact of Heavy Metals on Human Health in Conjunction with Modern Analytical Methods
por: Filipoiu, Dana Claudia, et al.
Publicado: (2022)

Micropulse Laser Therapy as an Integral Part of Eye Disease Management
por: Bodea, Flaviu, et al.
Publicado: (2023)

Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis
por: Behl, Tapan, et al.
Publicado: (2021)

Evaluation of the Phytochemistry–Therapeutic Activity Relationship for Grape Seeds Oil
por: Gitea, Manuel Alexandru, et al.
Publicado: (2023)

Oral Janus Kinase Inhibitor for the Treatment of Rheumatoid Arthritis: Tofacitinib
por: Ni, Han, et al.
Publicado: (2013)

Comorbidities, Associated Diseases, and Risk Assessment in COVID-19—A Systematic Review
por: Fitero, Andreea, et al.
Publicado: (2022)

Antioxidant and Hypoglycemic Potential of Essential Oils in Diabetes Mellitus and Its Complications
por: Bungau, Simona Gabriela, et al.
Publicado: (2023)

Emerging Insights into the Applicability of Essential Oils in the Management of Acne Vulgaris
por: Bungau, Alexa Florina, et al.
Publicado: (2023)

Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of Embelia ribes Burm.
por: Sharma, Vineet, et al.
Publicado: (2022)

The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis
por: Cojocaru, Lucia, et al.
Publicado: (2013)

Clinical, Pathological and Microbiological Evaluation of Diabetic Foot Syndrome
por: Uivaraseanu, Bogdan, et al.
Publicado: (2020)

Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis
por: Milici, Anthony J, et al.
Publicado: (2008)

Clinical Aspects of Janus Kinase (JAK) Inhibitors in the Cardiovascular System in Patients with Rheumatoid Arthritis
por: Kotyla, Przemysław J., et al.
Publicado: (2020)

Changes in the cholesterol profile of patients with rheumatoid arthritis treated with biologics or Janus kinase inhibitors
por: Koh, Jung Hee, et al.
Publicado: (2023)

Janus Kinase Inhibitors in Rheumatoid Arthritis: An Update on the Efficacy and Safety of Tofacitinib, Baricitinib and Upadacitinib
por: Harrington, Robert, et al.
Publicado: (2023)

Drug Retention Rates and the Safety of Janus Kinase Inhibitors in Elderly Patients with Rheumatoid Arthritis
por: Temmoku, Jumpei, et al.
Publicado: (2023)

The potential molecular implications of adiponectin in the evolution of SARS-CoV-2: Inbuilt tendency
por: Al-Kuraishy, Hayder M., et al.
Publicado: (2022)

Asymmetrically Nanostructured 2D Janus Films Obtained from Pickering Emulsions Polymerized in a Langmuir–Blodgett Trough
por: Honciuc, Andrei, et al.
Publicado: (2023)

Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study
por: Ebina, Kosuke, et al.
Publicado: (2023)

Drug Retention Rates of Janus Kinase Inhibitors in Rheumatoid Arthritis Patients with Therapy-Induced Lymphopenia
por: Temmoku, Jumpei, et al.
Publicado: (2023)

In Silico and In Vitro Study of Janus Kinases Inhibitors from Naphthoquinones
por: Sanachai, Kamonpan, et al.
Publicado: (2023)

Virtual screening of substances used in the treatment of SARS-CoV-2 infection and analysis of compounds with known action on structurally similar proteins from other viruses
por: Negru, Paul Andrei, et al.
Publicado: (2022)

Targeting Probiotics in Rheumatoid Arthritis
por: Bungau, Simona Gabriela, et al.
Publicado: (2021)

The Footprint of Kynurenine Pathway in Neurodegeneration: Janus-Faced Role in Parkinson’s Disorder and Therapeutic Implications
por: Behl, Tapan, et al.
Publicado: (2021)

Tofacitinib, an oral Janus kinase inhibitor: analysis of malignancies across the rheumatoid arthritis clinical development programme
por: Curtis, Jeffrey R, et al.
Publicado: (2016)

Tofacitinib, an Oral Janus Kinase Inhibitor: Pooled Efficacy and Safety Analyses in an Australian Rheumatoid Arthritis Population
por: Hall, Stephen, et al.
Publicado: (2018)

Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition
por: Dowty, Martin E., et al.
Publicado: (2019)

Risk of venous thromboembolism associated with Janus kinase inhibitors for rheumatoid arthritis: case presentation and literature review
por: Mori, Shunsuke, et al.
Publicado: (2021)

Factors affecting drug retention of Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study
por: Ebina, Kosuke, et al.
Publicado: (2022)

Cardiovascular safety of Janus kinase inhibitors in patients with rheumatoid arthritis: systematic review and network meta-analysis
por: Wei, Qige, et al.
Publicado: (2023)

Janus kinase inhibitors effectively improve pain across different disease activity states in rheumatoid arthritis
por: De Stefano, Ludovico, et al.
Publicado: (2023)

The Rare Condition of Left Ventricular Non-Compaction and Reverse Remodeling
por: Bustea, Cristiana, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h2ua8hl2kfhp6e1o18n2rmj46r